Results 81 to 90 of about 816,185 (299)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Towards an optimal tone space

, 2011
The utility of tones spaces based on tone productions can be judged on the degree to which they (i) differentiate tone productions and (ii) predict tone perception. Here based on a production corpus, 5 different 2-dimensional tone spaces are constructed.
Attina, Virginie (R14534), Xu, Nan (R13868), Burnham, Denis K. (R7357), Kasisopa, Benjawan (R17619)   +3 more
core  

Using of Wingeom Software in Geometry Learning to Improving the of Mathematical Representation Ability

Malikussaleh Journal of Mathematics Learning, 2019
The purpose of this study was to determine the use of Wingeom software in geometry learning in the Department of Mathematics Education. This type of research is quasi-experimental.
Mutia Fonna, M Mursalin
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Effects of representation sequences and spatial ability on students’ scientific understandings about the mechanism of breathing

, 2014
[[abstract]]The purpose of this study was to investigate the effects of representation sequences and spatial ability on students’ scientific understandings about the mechanism of breathing in human beings.
Wu, H.-K.;Lin, Y. F.;Hsu, Y. S.
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Analysis of Students' Mathematical Representation Ability in Terms of Resilience

This research aims to describe students' mathematical representation abilities in terms of mathematical resilience. The method used in this research is the descriptive method.
Herawati, Linda, Fatmasari, Yola, Rustina, Ratna   +2 more
core   +1 more source

Profiles of preschoolers’ numerical abilities across quantity representations.

Canadian Journal of Experimental Psychology / Revue canadienne de psychologie expérimentale
Children's early numerical abilities shape their trajectories for math learning throughout schooling, and task quantity representation (e.g., nonsymbolic vs. symbolic) affects their reasoning about numerical concepts. The role of quantity representation in early numerical ability has typically been studied using variable-centered approaches.
Brianna L. Devlin, Haobai Zhang, Amber Beliakoff, Dana Miller-Cotto, Alice Klein, Nancy C. Jordan   +5 more
openaire   +2 more sources

On the ability of visual representation of ideas and verbal contents

Культура и искусство, 2021
Using the examples of displayed works of art, painting and music, this article discusses the ability of visual representation of ideas and verbal contents. The author compares two stages in the development of art: the early XX century with the popular were popular ideas of cosmism and the advent of the new world; and the present time characterized by
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source