Results 41 to 50 of about 351,687 (262)

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba   +11 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Learning representations of learning representations

open access: yes
The ICLR conference is unique among the top machine learning conferences in that all submitted papers are openly available. Here we present the ICLR dataset consisting of abstracts of all 24 thousand ICLR submissions from 2017-2024 with meta-data, decision scores, and custom keyword-based labels.
González-Márquez, Rita, Kobak, Dmitry
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Knowledge Graphs in Education and Employability: A Survey on Applications and Techniques

open access: yesIEEE Access, 2022
Studies on the relationship between education and employability are of paramount importance for policy makers, training institutions, companies and students. The availability of large scale data on the Internet, such as online job ads, has been leveraged
Yousra Fettach   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Entity Profiling in Knowledge Graphs

open access: yesIEEE Access, 2020
Knowledge Graphs (KGs) are graph-structured knowledge bases storing factual information about real-world entities. Understanding the uniqueness of each entity is crucial to the analyzing, sharing, and reusing of KGs.
Xiang Zhang   +3 more
doaj   +1 more source

Self-Supervised Learning Methods for Label-Efficient Dental Caries Classification

open access: yesDiagnostics, 2022
High annotation costs are a substantial bottleneck in applying deep learning architectures to clinically relevant use cases, substantiating the need for algorithms to learn from unlabeled data.
Aiham Taleb   +7 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Research and development of network representation learning

open access: yes网络与信息安全学报, 2019
Network representation learning is a bridge between network raw data and network application tasks which aims to map nodes in the network to vectors in the low-dimensional space.These vectors can be used as input to the machine learning model for social ...
Ying YIN   +3 more
doaj   +3 more sources

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