Results 71 to 80 of about 833,337 (337)

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

The place of nature? Electoral politics and the Tasmanian Greens [PDF]

open access: yes, 2008
Green politics in Tasmania is very much a politics of place, driven by struggles to save iconic natural areas such as Lake Pedder, the Franklin River, the South West wilderness and more recently the state’s old growth forests and unprotected areas. These
Crowley, K
core   +2 more sources

Electing women to Parliament: Fiji and the alternative vote electoral system

open access: yesPacific Journalism Review, 2006
In many places in the world, women struggle to be heard and, when it comes to having a voice in the highest authority in the land, the difficulties in some countries can be almost insurmountable.
Rae Nicholl
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Etnisitas sebagai Instrumen Politik dan Keamanan di Kalimantan Barat Pasca Rezim Orde Baru [PDF]

open access: yes, 2013
Political changes of the New Order regime have an impact on the dynamics of local politics in West Kalimantan. These changes raise complex issues related to ethnic and religious issues in the rivalry between Dayak and Malay elite. Therefore, this article
Jumadi, J. (Jumadi)   +1 more
core  

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Race, Redistricting, and Representation [PDF]

open access: yes, 2007
This Essay, which was written for the Ohio State Law Journal\u27s symposium on Election Law and the Roberts Court, examines the Court\u27s decision in League of United Latin American Citizens (LULAC) v. Perry. The Essay explores two ways of reading LULAC:
Charles, Guy-Uriel
core   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

open access: yesFEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili   +2 more
wiley   +1 more source

O bacharel em direito como o homem público brasileiro

open access: yesMediações: Revista de Ciências Sociais, 2003
Law bachelors are, and always have been, the most widely represented class in brazilian politics. The constitution of the House of Representatives throughout history has reflected this reality since the Empire.
Humberto Dantas
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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