Results 71 to 80 of about 4,758,768 (384)

Westminster can learn a lot about gender equality by looking at Welsh and Scottish levels of political representation [PDF]

open access: yes, 2012
Discrimination and under-representation of women is still overt and visible in politics. Diana Silvia Stirbu argues that progress on the gender equality agenda doesn’t come easily, but it is possible through a combination of structural, political and ...
Stirbu, Diana Silvia
core  

School-based parents’ groups - a politics of voice and representation? [PDF]

open access: yes, 2000
In this paper we consider two discussion-based parents’ forums at two secondary schools. We ask whether such forums can be considered as part of the small, local associative mechanisms which theorists claim have the potential to encourage a more vibrant ...
Martin, Jane, Vincent, Carol
core   +2 more sources

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Two Cheers for Czech Democracy [PDF]

open access: yes, 2014
The paper discusses the state of Czech democracy and current research agendas on democracy in the Czech Republic, focusing in particular on the role of political parties.
Hanley, SL
core   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

The Impact of Electoral Gender Quotas on Women’s Political Participation in Bosnia and Herzegovina

open access: yesPolitics in Central Europe, 2023
Although representing half of the world population, women remain largely excluded from political power and government structures. Various strategies have been introduced to increase women’s political representation, including electoral gender quotas ...
Merdanović Ajla Van Heel   +1 more
doaj   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

open access: yesMolecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo   +11 more
wiley   +1 more source

« Mâle ou normal ? ». Incarnation et masculinité(s) du couple Hollande-Sarkozy dans la campagne présidentielle de 2012

open access: yesGenre, Sexualité et Société, 2013
After the French presidential election of 2007 with Ségolène Royal as one of the two main candidates, the last election appears as « back to normal » with two men as finalists.
Marlène Coulomb-Gully
doaj   +1 more source

Making differences: cities, NGOs and the cultural politics of development discourse [PDF]

open access: yes, 2002
This book chapter reveals the politics of representation underlying depictions of non-Western cities in the literature on third world development. Development discourse is preoccupied with imaginary differences and hierarchies, it argues, and the places ...
O'Coill, Carl
core  

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