Results 61 to 70 of about 273,179 (250)

On Representation in Information Theory

open access: yesInformation, 2011
Semiotics is widely applied in theories of information. Following the original triadic characterization of reality by Peirce, the linguistic processes involved in information—production, transmission, reception, and understanding—would all appear to be ...
Joseph E. Brenner
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

A Method for Weight Multiplicity Computation Based on Berezin Quantization

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2009
Let G be a compact semisimple Lie group and T be a maximal torus of G. We describe a method for weight multiplicity computation in unitary irreducible representations of G, based on the theory of Berezin quantization on G/T.
David Bar-Moshe
doaj   +1 more source

STABILITY PATTERNS IN REPRESENTATION THEORY

open access: yesForum of Mathematics, Sigma, 2015
We develop a comprehensive theory of the stable representation categories of several sequences of groups, including the classical and symmetric groups, and their relation to the unstable categories.
STEVEN V SAM, ANDREW SNOWDEN
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Two-Dimensional Theory of Scientific Representation [PDF]

open access: yesMetaphysics, 2013
Scientific representation is an interesting topic for philosophers of science, many of whom have recently explored it from different points of view. There are currently two competing approaches to the issue: cognitive and non-cognitive, and each of them ...
A Yaghmaie, H Sheikh Rezaee
doaj   +2 more sources

Representation theory of skew braces [PDF]

open access: yesInternational Journal of Group Theory
According to Letourmy and Vendramin, a representation of a skew brace is a pair of representations on the same vector space, one for the additive group and the other for the multiplicative group, that satisfies a certain compatibility condition ...
Yuta Kozakai, Cindy Tsang
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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