Results 81 to 90 of about 2,948,149 (327)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Modular Representation Theory of Symmetric Groups [PDF]

open access: yes, 2014
We review some recent advances in modular representation theory of symmetric groups and related Hecke algebras. We discuss connections with Khovanov-Lauda-Rouquier algebras and gradings on the blocks of the group algebras $F\Sigma_n$, which these ...
Kleshchev, Alexander
core  

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Entropy of Entanglement between Quantum Phases of a Three-Level Matter-Radiation Interaction Model

open access: yesEntropy, 2018
We show that the entropy of entanglement is sensitive to the coherent quantum phase transition between normal and super-radiant regions of a system of a finite number of three-level atoms interacting in a dipolar approximation with a one-mode ...
Luis Fernando Quezada   +1 more
doaj   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Um Referente Fora de Foco: Sobre a Representatividade do Sindicalismo no Brasil

open access: yesDados: Revista de Ciências Sociais, 1997
In the academic debate, Brazilian unionism has been characterized both as representative and as non-representative – with defenders of both positions grounding their arguments in the same basic facts.
Adalberto Moreira Cardoso
doaj   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

Elementary properties of non-Linear Rossby-Haurwitz planetary waves revisited in terms of the underlying spherical symmetry

open access: yesAIMS Mathematics, 2019
We revisit Rossby-Haurwitz planetary wave modes of a two-dimensional fluid along the surface of a rotating planet, as elements of irreducible representations of the so(3) Lie algebra.
Ramses van der Toorn
doaj   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

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