Advanced Science, EarlyView.An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang +9 more
wiley +1 more source
Programmable transcriptional condensates for enhanced CRISPR-based gene regulation. [PDF]
TheranosticsLi A, Cao C, Yang C, Liu Y.
europepmc +1 more source
From parasite chromatin to host immune reprogramming: linking developmental state, effector regulation, and persistence in <i>Toxoplasma gondii</i>. [PDF]
Front ImmunolKim Y, Ham YS, Yun J, Han S, Yang CS.
europepmc +1 more source
The <i>FaAP2-11</i> Transcription Factor Putatively Regulates Cell Wall Remodeling and Stress-Acclimation Responses Under Drought and Salinity Stress. [PDF]
Int J Mol SciMoreno-Recio MD +11 more
europepmc +1 more source
Design guide for synthetic small regulatory RNAs for high-efficiency gene knockdown in bacteria. [PDF]
J MicrobiolRen J, Kim Y, Nam HJ, Lee HM, Na D.
europepmc +1 more source
SNCA-targeted transcriptional repression therapy alleviates pathological and behavioral perturbations in a Parkinson's disease mouse model. [PDF]
NeurotherapeuticsO'Donovan B +5 more
europepmc +1 more source
The Nuclear Interactome of ATR7 Implicates a Chromatin-Based Repression Mechanism Controlling Oxidative Stress Tolerance and Programmed Cell Death in Arabidopsis. [PDF]
Int J Mol SciQureshi MK, Gechev T.
europepmc +1 more source