Results 281 to 290 of about 855,140 (389)

Reversal of Stress‐Induced PIEZO1 Elevation with Mechanically Adapted Epicardial Patch for Myocardial Infarction Treatment

open access: yesAdvanced Science, EarlyView.
This work identifies fine‐tuning the expression of PIEZO1 as a critical molecular mechanism underlying the treatment of myocardial infarction by mechanically adapted cardiac patches, which can support the clinical translation of cardiac patch devices.
Yuwen Lu   +18 more
wiley   +1 more source

The immune NIK1/RPL10/LIMYB signaling module regulates photosynthesis and translation under biotic and abiotic stresses. [PDF]

open access: yesNat Commun
Ferreira MA   +16 more
europepmc   +1 more source

Catabolite Repression

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1961
openaire   +2 more sources

The TET3/GATA6 Axis Drives Lipid Metabolism and Therapeutic Vulnerabilities in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
The DNA demethylase TET3 drives lipid metabolic reprogramming in pancreatic ductal adenocarcinoma via a non‐catalytic mechanism. TET3 recruits histone deacetylases to repress GATA6, sustaining lipogenic enzyme expression and ferroptosis resistance.
Shuai Liu   +8 more
wiley   +1 more source

Therapy-induced senescence of glioblastoma cells is determined by the p21<sup>CIP1</sup>-CDK1/2 axis and does not require activation of DREAM. [PDF]

open access: yesCell Death Dis
Schwarzenbach C   +10 more
europepmc   +1 more source

A Novel OsMPK6‐OsMADS47‐PPKL1/3 Module Controls Grain Shape and Yield in Rice

open access: yesAdvanced Science, EarlyView.
OsMADS47 is identified as a key regulator governing rice grain morphology. Phosphorylation‐dependent regulation of its activity directs the development of slender versus round grains, modulating both yield and appearance. This mechanism bridges cellular signaling with transcriptional regulation, establishing a molecular framework for grain optimization.
Jingjing Fang   +9 more
wiley   +1 more source

The New State of the Art: Cas9 for Gene Activation and Repression

open access: yesMolecular and Cellular Biology, 2015
Marie La Russa, Lei S. Qi
semanticscholar   +1 more source

Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy

open access: yesAdvanced Science, EarlyView.
This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao   +8 more
wiley   +1 more source

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