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SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

open access: yesAdvanced Science, EarlyView.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo   +3 more
wiley   +1 more source

Functional microRNA targeting without seed pairing. [PDF]

open access: yesNucleic Acids Res
Hall MH, Wang PY, Pham TM, Bartel DP.
europepmc   +1 more source

YAP/TAZ-VGLL3 governs adipocyte fate via epigenetic reprogramming of PPARγ and its target enhancers. [PDF]

open access: yesSci Adv
Seol T   +11 more
europepmc   +1 more source

A human-specific regulatory mechanism revealed in a pre-implantation model. [PDF]

open access: yesNature
Fueyo R   +5 more
europepmc   +1 more source

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