Results 101 to 110 of about 297,096 (313)

Exploring Processes and Dynamics of Mystical Contemplative Meditation: Some Christian-Buddhist Parallels in Relation to Transpersonal Theory [PDF]

, 2015
This paper explores Christian contemplative meditation, focusing on the prayer of Recollection as it is developed especially by Evelyn Underhill and St. Teresa of Avila. It outlines the practice and explores possible theoretical and therapeutic dynamics,
Stoeber, Michael
core   +1 more source

DDX3 depletion selectively represses translation of structured mRNAs [PDF]

, 2019
DDX3 is an RNA chaperone of the DEAD-box family that regulates translation. Its yeast ortholog Ded1 controls the translation of nearly all mRNAs, whereas DDX3 is thought to regulate only a subset of mRNAs. However, the set of mRNAs that are regulated by DDX3 are unknown, along with the relationship between DDX3 binding and activity.
Calviello, Lorenzo, Venkataramanan, Srivats, Rogowski, Karol J., Wyler, Emanuel, Tejura, Malvika, Thai, Bao, Krol, Jacek, Filipowicz, Witold, Landthaler, Markus, Floor, Stephen N.   +9 more
openaire   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Silencing motifs in the Clr2 protein from fission yeast, Schizosaccharomyces pombe. [PDF]

PLoS ONE, 2014
The fission yeast, Schizosaccharomyces pombe, is a well-established model for heterochromatin formation, but the exact sequence of events for initiation remains to be elucidated.
Daniel Steinhauf, Alejandro Rodriguez, Dimitrios Vlachakis, Gordon Virgo, Vladimir Maksimov, Carolina Kristell, Ida Olsson, Tomas Linder, Sophia Kossida, Erik Bongcam-Rudloff, Pernilla Bjerling   +10 more
doaj   +1 more source

MORC3, a component of PML nuclear bodies, has a role in restricting herpes simplex virus type 1 and human cytomegalovirus [PDF]

, 2016
We previously reported that MORC3, a protein associated with promyelocytic leukemia nuclear bodies (PML NBs), is a target of HSV-1 ICP0 mediated degradation.
Everett, Roger, Orr, Anne, Sloan, Elizabeth   +2 more
core   +1 more source

Activation and repression of transcription initiation by a distant DNA structural transition [PDF]

Molecular Microbiology, 2001
Negative superhelical tension can drive local transitions to alternative DNA structures. Long regions of DNA may contain several sites that are susceptible to forming alternative structures. Their relative propensities to undergo transition are ordered according to the energies required for their formation.
S D, Sheridan, M L, Opel, G W, Hatfield
openaire   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Functional characterization of hexokinases in the moss Physcomitrella patens [PDF]

, 2005
Carbohydrates are important nutrients and structural components in all living organisms. In plants they affect the developmental and metabolic processes throughout the plant life cycle.
Olsson, Tina
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

KGB against former political prisoners and deportees

Genocidas ir Rezistencija, 2008
The Soviet totalitarian regime sought to crush and destroy the real and potential enemies of the new regime through mass repression in Lithuania between 1940 and 1953.
Kristina Burinskaitė
doaj   +1 more source