Results 31 to 40 of about 92,184 (310)
eLife, 2017 Ring-forming AAA+ chaperones exert ATP-fueled substrate unfolding by threading through a central pore. This activity is potentially harmful requiring mechanisms for tight repression and substrate-specific activation.
Marta Carroni +10 more
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Structural insights into gene repression by the orphan nuclear receptor SHP [PDF]
Proceedings of the National Academy of Sciences, 2013 Significance The orphan nuclear receptor small heterodimer partner (SHP) serves as a central regulator of bile acid and cholesterol homeostasis via its transcriptional repression activity. Yet little is known about SHP structure and its mechanism of corepressor recruitment.
Xiaoyong, Zhi +8 more
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PLoS ONE, 2016 Heterochromatinisation of pericentromeres, which in mice consist of arrays of major satellite repeats, are important for centromere formation and maintenance of genome stability.
Theona Natisvili +6 more
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EZH2 regulates neuroepithelium structure and neuroblast proliferation by repressing p21 [PDF]
Open Biology, 2016 The function of EZH2 as a transcription repressor is well characterized. However, its role during vertebrate development is still poorly understood, particularly in neurogenesis. Here, we uncover the role of EZH2 in controlling the integrity of the neural tube and allowing proper progenitor proliferation.
Naiara Akizu +6 more
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Structure and dynamics of the quaternary hunchback mRNA translation repression complex
Nucleic Acids Research, 2021 Abstract A key regulatory process during Drosophila development is the localized suppression of the hunchback mRNA translation at the posterior, which gives rise to a hunchback gradient governing the formation of the anterior-posterior body axis.
Jakub Macošek +16 more
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Germany Democratic Republic and Polish National Republic political polices
Genocidas ir Rezistencija, 2006 The Soviet regime needed to establish security structures in the satellite states. Due to the weak satellite communist parties (further weakened by Stalin’s repression), the Soviet regime had no confidence in its allies.
Kazimierz Woycicki
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Cells, 2020 Chromosomes are organized into 3D structures that are important for the regulation of gene expression and differentiation. Important role in formation of inter-chromosome contacts play rDNA clusters that make up nucleoli. In the course of differentiation,
Nickolai A. Tchurikov +7 more
doaj +1 more source
Repression and Protest Structural Models and Strategic Interactions [PDF]
Revue française de science politique (English), 2013 Abstract The recent wave of upheavals and revolts in Northern Africa and the Middle East goes back to an old question often raised by theories of collective action: does repression act as a negative or positive incentive for further mobilization?
Hélène Combes +2 more
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Detection and functional characterization of a 215 amino acid N-terminal extension in the Xanthomonas type III effector XopD. [PDF]
PLoS ONE, 2010 During evolution, pathogens have developed a variety of strategies to suppress plant-triggered immunity and promote successful infection. In Gram-negative phytopathogenic bacteria, the so-called type III protein secretion system works as a molecular ...
Joanne Canonne +7 more
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Estrogen represses gene expression through reconfiguring chromatin structures [PDF]
Nucleic Acids Research, 2013 Estrogen regulates over a thousand genes, with an equal number of them being induced or repressed. The distinct mechanisms underlying these dual transcriptional effects remain largely unknown. We derived comprehensive views of the transcription machineries assembled at estrogen-responsive genes through integrating multiple types of genomic data. In the
Osmanbeyoglu, Hatice Ulku +6 more
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