Results 91 to 100 of about 308,170 (360)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

On handling urban informality in southern Africa [PDF]

open access: yes, 2013
In this article I reconsider the handling of urban informality by urban planning and management systems in southern Africa. I argue that authorities have a fetish about formality and that this is fuelled by an obsession with urban modernity.
AAPS   +83 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Problem of juridical evaluation of MGB agents combatant

open access: yesGenocidas ir Rezistencija, 2004
This article focuses on the coordinated efforts of various authorities to investigate the cases of agents–hitmen, the difficulties encountered, and the ways of serving justice.
Saulius Samulevičius
doaj   +1 more source

Between emancipation and domination: Habermasian reflections on the empowerment and disempowerment of the human subject [PDF]

open access: yes, 2009
Habermas’s ‘linguistic turn’ can be regarded as a systematic attempt to locate the normative foundations of critical theory in the rational foundations of language.
Susen, Simon
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Promoting global Internet freedom: policy and technology [PDF]

open access: yes, 2012
This report provides information about US government and private sector efforts to promote and support global Internet freedom and a description of Internet freedom legislation and hearings from the 112th Congress.
Patricia Moloney Figliola
core   +6 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A repressive H3K36me2 reader mediates Polycomb silencing

open access: yesNature Communications
In animals, evolutionarily conserved Polycomb repressive complex 2 (PRC2) catalyzes histone H3 lysine 27 trimethylation (H3K27me3) and PRC1 functions in recruitment and transcriptional repression.
Mengting Xu   +7 more
doaj   +1 more source

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