Results 151 to 160 of about 308,170 (360)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Den allmänna repressionsnivån och brottens relativa allvar
Nordisk Tidsskrift for KriminalvidenskabA recently proposed overhaul of Swedish criminal law is characte rized by calls for punitive reforms. The government cites changes in the perception of the severity of different crimes, the appropriate general level of repression, the balance between the
Sigrid Nikka
doaj +1 more source
Legal socialization effects on democratization [PDF]
, 1997 As is the case with all our joint publications, this article represents a genuine research collaboration between the authors, with equal contributions. Therefore, neither is first or second author. This article uses data from a collaborative project that
Cohn, Ellen S, White, Susan O
core +2 more sources
Histone acetylation: a switch between repressive and permissive chromatin [PDF]
, 2002 Anton Eberharter, Peter B. Becker
openalex +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Functional Characterization of an Amino-terminal Region of HDAC4 That Possesses MEF2 Binding and Transcriptional Repressive Activity [PDF]
, 2003 Jonathan Chan +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source