Results 31 to 40 of about 308,170 (360)
PLoS Genetics, 2014 Friedreich ataxia (FRDA) and Fragile X syndrome (FXS) are among 40 diseases associated with expansion of repeated sequences (TREDs). Although their molecular pathology is not well understood, formation of repressive chromatin and unusual DNA structures ...
Matthias Groh +3 more
doaj +1 more source
Hybris, 2020 The purpose of the article is to demonstrate that Freud's theory in its late, mature form significantly goes beyond the model associated with the "repressive hypothesis" and thus can potentially be a useful conceptual tool for analyzing the contemporary ...
Antoni Grzybowski
doaj +1 more source
dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression. [PDF]
, 2017 Distinct epigenomic profiles of histone marks have been associated with gene expression, but questions regarding the causal relationship remain. Here we investigated the activity of a broad collection of genomically targeted epigenetic regulators that ...
Farnham, Peggy J +8 more
core +2 more sources
Review essay: Disentangling feminisms from the cold war [PDF]
, 2020 Feminist thinkers have long argued for the centrality of sexuality, gender and women to the Cold War. They have critiqued the sexual language of ‘deep penetration’ and ‘orgasmic whumps’ used to describe nuclear arms race technology and argued that ...
Bellows-Blakely, Sarah
core +1 more source
Definition of functionally and structurally distinct repressive states in the nuclear receptor PPARγ
Nature Communications, 2019 The repressive states of peroxisome proliferator-activated receptor γ (PPARγ) are ill-defined, despite nuclear receptors being a major drug target.
Zahra Heidari +10 more
doaj +1 more source
The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state [PDF]
, 2016 Indexación: Web of ScienceWith about 350 million people chronically infected around the world hepatitis B is a major health problem. Template for progeny HBV synthesis is the viral genome, organized as a minichromosome (cccDNA) inside the hepatocyte ...
Alarcon, V +9 more
core +2 more sources
Insomnia symptoms and repressive coping in a sample of older Black and White women
BMC Women's Health, 2007 Background This study examined whether ethnic differences in insomnia symptoms are mediated by differences in repressive coping styles. Methods A total of 1274 women (average age = 59.36 ± 6.53 years) participated in the study; 28% were White and 72 ...
Pierre-Louis Jessy +6 more
doaj +1 more source
Reading Social Criticism of Tuk Drama in Richard Schechner’s Ac Diagram Perspective [PDF]
, 2012 The main problem of this research is social criticism in the drama written in New Order era which was in repressive, authoritarian, and corruptive social political conditions.
NUR, SAHID
core
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
The LINC Complex Inhibits Excessive Chromatin Repression
Cells, 2023 The Linker of Nucleoskeleton and Cytoskeleton (LINC) complex transduces nuclear mechanical inputs suggested to control chromatin organization and gene expression; however, the underlying mechanism is currently unclear.
Daria Amiad Pavlov +8 more
doaj +1 more source