Results 61 to 70 of about 308,170 (360)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
Nuevo mundo - Mundos Nuevos, 2018 In this article, we will analyze the relationship between labor discipline and forms of repression against workers during the last military dictatorship in Argentina (1976-1983). We focus specifically on the repressive modalities directed towards workers,
Ana Belén Zapata
doaj +1 more source
The persistence of media control under consolidated authoritarianism: containing Kazakhstan’s digital media [PDF]
, 2015 Citizens of Kazakhstan have greater access to the Internet now than at any time in the past. However, the Nazarbaev regime has systematically cut off the supply of political analysis on the country's web sites while simultaneously shifting popular on ...
Anceschi, Luca
core
New insights into the epigenetic control of satellite cells [PDF]
, 2015 Epigenetics finely tunes gene expression at a functional level without modifying the DNA sequence, thereby contributing to the complexity of genomic regulation.
Adamo, Sergio +2 more
core +1 more source
From ‘the effect of repression’ toward ‘the response to repression’ [PDF]
Current Sociology, 2018 Scholars have long been interested in explaining the effect of state repression on political participation. Recent reviews of research on state repression highlighted contradictory findings about this effect, yet the core question is still debated: what accounts for the variation in the effects of repression?
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti +12 more
wiley +1 more source
Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing. [PDF]
, 2020 Mammalian circadian rhythms are generated by a transcription-based feedback loop in which CLOCK:BMAL1 drives transcription of its repressors (PER1/2, CRY1/2), which ultimately interact with CLOCK:BMAL1 to close the feedback loop with ~24 hr periodicity ...
Abraham +70 more
core +3 more sources
MYC in elongation and repression [PDF]
Nature Reviews Cancer, 2018 Transcription elongation supported by the super elongation complex, and H3K9 methylation and gene repression by G9a mediate the oncogenic function of Myc.
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider +4 more
wiley +1 more source
Differential modulation of polycomb-associated histone marks by cBAF, pBAF, and gBAF complexes
Life Science AllianceThis study shows that the canonical BAF (cBAF) complex uniquely opposes polycomb-associated repressive marks at the Nkx2-9 gene in mouse embryonic stem cells, leading to transcriptional activation, a function not shared by gBAF or pBAF complexes ...
Mary Bergwell +2 more
doaj +1 more source