Results 131 to 140 of about 30,544 (313)
Toward enacting a Zapatista feminist agenda somewhere in la Selva Lacondona: We are all Marias?
Cogent Arts & Humanities, 2018 Women’s participation in the Zapatista Revolutionary Movement improved women’s potential for gender justice as outlined in the 1994 Declaration of Women’s Rights; however, Zapatismo has struggled to implement and sustain a clear indigenous feminist ...
Mary Louisa Cappelli
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Many diversities for many customers: contextualizing diversity (management) in four service companies. [PDF]
Diversity studies generally define diversity by referring to one or more employees' demographic traits such as gender, race, ethnicity, and age, and examine subsequently the effects of these differences onto a variety of organizational practices and ...
Janssens, Maddy, Zanoni, Patrizia
core
Ideological Apologetics of the Communist Party in Suppressing National Resistance (1944–1953)
Genocidas ir Rezistencija, 2004 After the Second World War, Lithuania suffered one of the most terrible periods in the country's history. Repressive structures were dominant. The restored party and government institutions tolerated this situation, because they considered the growing ...
Juozapas Romualdas Bagušauskas
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
R-loops induce repressive chromatin marks over mammalian gene terminators.
, 2014 The formation of R-loops is a natural consequence of the transcription process, caused by invasion of the DNA duplex by nascent transcripts. These structures have been considered rare transcriptional by-products with potentially harmful effects on genome
Kamieniarz-Gdula, Kinga +4 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Rb-mediated chromatin structure regulation and transcriptional repression [PDF]
Oncogene, 2001 H S, Zhang, D C, Dean
openaire +2 more sources