Accuracy of ChatGPT and DeepSeek in answering clinical questions from the 2025 Society for Cardiovascular Angiography & Interventions/Heart Rhythm Society left atrial appendage occlusion guidelines. [PDF]
Jin Y, Feng C, Zhao J, Lin W, Li B.
europepmc +1 more source
Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer +3 more
wiley +1 more source
Precision Diffusion-Weighted Imaging of Head and Neck Squamous Cell Carcinoma. [PDF]
Guzmán Pérez-Carrillo GJ +11 more
europepmc +1 more source
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai +13 more
wiley +1 more source
Modeling <i>APOE</i>, morbidity, and mortality: a reproducibility challenge for genetic epidemiology. [PDF]
Häggström Gunfridsson E.
europepmc +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Determination of the Same Cardiac Cycle When Analyzing Cine Clips for Use by FetalHQ to Assess Intraobserver and Interobserver Variability. Comment on Mlodawski et al. Reproducibility Challenges in Fetal Cardiac Function Analysis with 2D Speckle-Tracking Echocardiography: Insights from FetalHQ. <i>J. Clin. Med.</i> 2025, <i>14</i>, 3301. [PDF]
DeVore GR.
europepmc +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Enhancing rigor and reproducibility: Implementing STAR Methods and the ISSCR Standards Checklist at Stem Cell Reports. [PDF]
Rossant J.
europepmc +1 more source

