Results 21 to 30 of about 1,172,231 (143)
The Reproducibility of Lists of Differentially Expressed Genes in Microarray Studies [PDF]
, 2007 Reproducibility is a fundamental requirement in scientific experiments and clinical contexts. Recent publications raise concerns about the reliability of microarray technology because of the apparent lack of agreement between lists of differentially ...
Brett Thorn +49 more
core +2 more sources
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Sessile Legionella pneumophila is able to grow on surfaces and generate structured monospecies biofilms [PDF]
, 2010 Currently, models for studying Legionella pneumophila biofilm formation rely on multi-species biofilms with low reproducibility or on growth in rich medium, where planktonic growth is unavoidable.
Bergé, Mathieu +3 more
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The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Selection and use of TLDS for high precision NERVA shielding measurements [PDF]
, 1972 An experimental evaluation of thermoluminescent dosimeters was performed in order to select high precision dosimeters for a study whose purpose is to measure gamma streaming through the coolant passages of a simulated flight type internal NERVA reactor ...
Woodsum, H. C.
core +1 more source
Stabilization of an AM mode-locked tea CO2 laser [PDF]
, 1983 An increased shot-to-shot reproducibility has been obtained by injection of radiation from a cw CO2 laser in an amplitude mode-locked TEA CO2 laser without additional pulse broadening.
Goor, F.A. van
core +3 more sources
FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
Reproducibility Performance Test of Multi Metal Oxide Catalyst in Selective Oxidation of Propane using Combinatorial Technology [PDF]
, 2014 The concept of rapid catalyst screening using combinatorial technology was applied in the development of selective oxidation catalyst. In this paper, the design, Design of Experiment (DOE) and catalytic results are discussed to demonstrate the ...
Abd Hamid, Sharifah Bee +1 more
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Inflammatory and angiogenic protein detection in the human vitreous : cytometric bead assay [PDF]
, 2011 Introduction. To evaluate clinical feasibility and reproducibility of cytometric bead assay (CBA) in nondiluted vitreous samples of patients with age-related macular degeneration (ARMD), diabetic macular edema (DME), and central retinal vein occlusion ...
Koch, Frank H. +2 more
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