Results 21 to 30 of about 690,617 (311)

Reproducibility blues [PDF]

The EMBO Journal, 2015
Research findings advance science only if they are significant, reliable and reproducible. Scientists and journals must publish robust data in a way that renders it optimally reproducible. Reproducibility has to be incentivized and supported by the research infrastructure but without dampening innovation.
openaire   +2 more sources

Registered report: Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

eLife, 2014
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
David Blum, Samuel LaBarge, Reproducibility Project: Cancer Biology   +2 more
doaj   +1 more source

Registered report: Widespread potential for growth factor-driven resistance to anticancer kinase inhibitors

eLife, 2014
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
Edward Greenfield, Erin Griner, Reproducibility Project: Cancer Biology   +2 more
doaj   +1 more source

Registered report: the microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

eLife, 2015
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers,
Jia Li, Matthew Lam, Reproducibility Project: Cancer Biology   +2 more
doaj   +1 more source

Registered report: Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

eLife, 2015
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers,
Brad Evans, Erin Griner, Reproducibility Project: Cancer Biology   +2 more
doaj   +1 more source

Realising Open Data Principles In UK Research Institutions

International Journal of Digital Curation
We report on the state of open research data (ORD) policy and practice across UK research institutions through the STAR (Sustainable & TrAnsparent Research data) project. Through qualitative interviews, focus groups, and workshops involving 52 university
Pen-Yuan Hsing, Jessica Wheeler, Lorna Duncan, Rosalind Strang, Neil Jacobs   +4 more
doaj   +1 more source

Convolutional Neural Network Addresses the Confounding Impact of CT Reconstruction Kernels on Radiomics Studies

Tomography, 2021
Achieving high feature reproducibility while preserving biological information is one of the main challenges for the generalizability of current radiomics studies.
Jin H. Yoon, Shawn H. Sun, Manjun Xiao, Hao Yang, Lin Lu, Yajun Li, Lawrence H. Schwartz, Binsheng Zhao   +7 more
doaj   +1 more source

Using Mice to Model Human Disease: Understanding the Roles of Baseline Housing-Induced and Experimentally Imposed Stresses in Animal Welfare and Experimental Reproducibility

Animals, 2022
Mice are the most common animal used to study disease, but there are real concerns about the reproducibility of many of these experiments. This review discusses how several different sources of chronic stress can directly impact experimental outcomes ...
Bonnie L. Hylander, Elizabeth A. Repasky, Sandra Sexton   +2 more
doaj   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

Research rigor and reproducibility in research education: A CTSA institutional survey

Journal of Clinical and Translational Science
We assessed the rigor and reproducibility (R&R) activities of institutions funded by the National Center for Advancing Translational Sciences (NCTSA) through a survey and website search (N = 61).
Cathrine Axfors, Mario Malički, Steven N. Goodman   +2 more
doaj   +1 more source