Results 31 to 40 of about 1,263,629 (290)

Reproducibility of electrical caries measurements: A technical problem? [PDF]

open access: yes, 2005
The currently available instrument for electrical detection of occlusal caries lesions {[}Electronic Caries Monitor (ECM)] uses a site-specific measurement with co-axial air drying. The reproducibility of this method has been reported to be fair to good.
Huysmans, Marie-Charlotte D. N. J. M.   +2 more
core   +2 more sources

Registered report: Widespread potential for growth factor-driven resistance to anticancer kinase inhibitors

open access: yeseLife, 2014
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
Edward Greenfield   +2 more
doaj   +1 more source

Measuring reproducibility of high-throughput experiments

open access: yes, 2011
Reproducibility is essential to reliable scientific discovery in high-throughput experiments. In this work we propose a unified approach to measure the reproducibility of findings identified from replicate experiments and identify putative discoveries ...
Bickel, Peter J.   +3 more
core   +1 more source

Registered report: the microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

open access: yeseLife, 2015
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers,
Jia Li   +2 more
doaj   +1 more source

Registered report: Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

open access: yeseLife, 2015
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers,
Brad Evans   +2 more
doaj   +1 more source

A systematic review of methods to immobilise breast tissue during adjuvant breast irradiation [PDF]

open access: yes, 2013
Greater use of 3D conformal, Intensity Modulated Radiotherapy (IMRT) and external beam partial breast irradiation following local excision (LE) for breast cancer has necessitated a review of the effectiveness of immobilisation methods to stabilise breast
Barrett-Lennard   +48 more
core   +1 more source

Realising Open Data Principles In UK Research Institutions

open access: yesInternational Journal of Digital Curation
We report on the state of open research data (ORD) policy and practice across UK research institutions through the STAR (Sustainable & TrAnsparent Research data) project. Through qualitative interviews, focus groups, and workshops involving 52 university
Pen-Yuan Hsing   +4 more
doaj   +1 more source

Convolutional Neural Network Addresses the Confounding Impact of CT Reconstruction Kernels on Radiomics Studies

open access: yesTomography, 2021
Achieving high feature reproducibility while preserving biological information is one of the main challenges for the generalizability of current radiomics studies.
Jin H. Yoon   +7 more
doaj   +1 more source

On the Reproducibility of TCGA Ovarian Cancer MicroRNA Profiles [PDF]

open access: yes, 2013
Dysregulated microRNA (miRNA) expression is a well-established feature of human cancer. However, the role of specific miRNAs in determining cancer outcomes remains unclear.
Allen, Genevera   +4 more
core   +3 more sources

Using Mice to Model Human Disease: Understanding the Roles of Baseline Housing-Induced and Experimentally Imposed Stresses in Animal Welfare and Experimental Reproducibility

open access: yesAnimals, 2022
Mice are the most common animal used to study disease, but there are real concerns about the reproducibility of many of these experiments. This review discusses how several different sources of chronic stress can directly impact experimental outcomes ...
Bonnie L. Hylander   +2 more
doaj   +1 more source

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