Results 31 to 40 of about 697,667 (267)

Convolutional Neural Network Addresses the Confounding Impact of CT Reconstruction Kernels on Radiomics Studies

Tomography, 2021
Achieving high feature reproducibility while preserving biological information is one of the main challenges for the generalizability of current radiomics studies.
Jin H. Yoon, Shawn H. Sun, Manjun Xiao, Hao Yang, Lin Lu, Yajun Li, Lawrence H. Schwartz, Binsheng Zhao   +7 more
doaj   +1 more source

Using Mice to Model Human Disease: Understanding the Roles of Baseline Housing-Induced and Experimentally Imposed Stresses in Animal Welfare and Experimental Reproducibility

Animals, 2022
Mice are the most common animal used to study disease, but there are real concerns about the reproducibility of many of these experiments. This review discusses how several different sources of chronic stress can directly impact experimental outcomes ...
Bonnie L. Hylander, Elizabeth A. Repasky, Sandra Sexton   +2 more
doaj   +1 more source

Solving reproducibility [PDF]

Science, 2015
The reproducibility problem in science is a familiar issue, not only within the scientific community, but with the general public as well. Recent developments in social psychology (such as fraudulent research by D. Stapel) and cell biology (the Amgen Inc.
uploaded via Dissemin, Stuart Buck
openaire   +2 more sources

Reproducible Containers [PDF]

Proceedings of the Twenty-Fifth International Conference on Architectural Support for Programming Languages and Operating Systems, 2020
We describe the design and implementation of DetTrace, a reproducible container abstraction for Linux implemented in user space. All computation that occurs inside a DetTrace container is a pure function of the initial filesystem state of the container.
Omar S. Navarro Leija, Kelly Shiptoski, Ryan G. Scott, Baojun Wang, Nicholas Renner, Ryan R. Newton, Joseph Devietti   +6 more
openaire   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Research rigor and reproducibility in research education: A CTSA institutional survey

Journal of Clinical and Translational Science
We assessed the rigor and reproducibility (R&R) activities of institutions funded by the National Center for Advancing Translational Sciences (NCTSA) through a survey and website search (N = 61).
Cathrine Axfors, Mario Malički, Steven N. Goodman   +2 more
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Reproducibility as a service

Software: Practice and Experience, 2023
AbstractRecent studies demonstrated that the reproducibility of previously published computational experiments is inadequate. Many of these published computational experiments never recorded or preserved their computational environment, including packages installed in the language, libraries installed on the host system, and file locations. Researchers
Joseph Wonsil, Nichole Boufford, Prakhar Agrawal, Christopher Chen, Tianhang Cui, Akash Sivaram, Margo I. Seltzer   +6 more
openaire   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source