Results 41 to 50 of about 1,534,989 (367)

Addressing variability in iPSC-derived models of human disease: guidelines to promote reproducibility

Disease Models & Mechanisms, 2020
Induced pluripotent stem cell (iPSC) technologies have provided in vitro models of inaccessible human cell types, yielding new insights into disease mechanisms especially for neurological disorders.
Viola Volpato, C. Webber
semanticscholar   +1 more source

Replication Study: The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

eLife, 2017
In 2015, as part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Chroscinski et al., 2015) that described how we intended to replicate selected experiments from the paper “The CD47-signal regulatory protein alpha (SIRPa)
Stephen K Horrigan, Reproducibility Project: Cancer Biology   +1 more
doaj   +1 more source

Effects of grouped versus alternating functional training on the shoulder girdle and lumbar-pelvic girdle stability: a randomised controlled trial

Motricidade, 2022
The present research aimed to verify the effect of 10 weeks of structured FT grouped by muscular actions (GFT) or alternating actions (AFT) on scapular and lumbar-pelvic girdle stability.
Marzo da Silva-Grigoletto, José C. Aragão-Santos, Alan S. Fontes, Marta S. Santos, Antônio G. Resende-Neto, Marcos Raphael Pereira Monteiro, Edilson Serpeloni Cyrino, Pedro J. Marin, David G. Behm   +8 more
doaj   +1 more source

Artificial intelligence faces reproducibility crisis.

Science, 2018
The booming field of artificial intelligence (AI) is grappling with a replication crisis, much like the ones that have afflicted psychology, medicine, and other fields over the past decade.
M. Hutson
semanticscholar   +1 more source

Challenges to the Reproducibility of Machine Learning Models in Health Care.

Journal of the American Medical Association (JAMA), 2020
Reproducibility has been an important and intensely debated topic in science and medicine for the past few decades.1 As the scientific enterprise has grown in scope and complexity, concerns regarding how well new findings can be reproduced and validated ...
Andrew Beam, A. Manrai, M. Ghassemi
semanticscholar   +1 more source

Registered report: the microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

eLife, 2015
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers,
Jia Li, Matthew Lam, Reproducibility Project: Cancer Biology   +2 more
doaj   +1 more source

Mitigation Strategies to Improve Reproducibility of Poverty Estimations From Remote Sensing Images Using Deep Learning

Earth and Space Science, 2022
The challenges of Reproducibility and Replicability (R & R) in computer science experiments have become a focus of attention in the last decade, as efforts to adhere to good research practices have increased. However, experiments using Deep Learning (DL)
J. Machicao, A. Ben Abbes, L. Meneguzzi, P. L. P. Corrêa, A. Specht, R. David, G. Subsol, D. Vellenich, R. Devillers, S. Stall, N. Mouquet, M. Chaumont, L. Berti‐Equille, D. Mouillot   +13 more
doaj   +1 more source

Variability and reproducibility of multi-echo T2 relaxometry: Insights from multi-site, multi-session and multi-subject MRI acquisitions

Frontiers in Radiology, 2022
Quantitative magnetic resonance imaging (qMRI) can increase the specificity and sensitivity of conventional weighted MRI to underlying pathology by comparing meaningful physical or chemical parameters, measured in physical units, with normative values ...
Elda Fischi-Gomez, Elda Fischi-Gomez, Gabriel Girard, Gabriel Girard, Gabriel Girard, Philipp J. Koch, Philipp J. Koch, Philipp J. Koch, Philipp J. Koch, Thomas Yu, Thomas Yu, Marco Pizzolato, Marco Pizzolato, Julia Brügger, Julia Brügger, Gian Franco Piredda, Gian Franco Piredda, Gian Franco Piredda, Tom Hilbert, Tom Hilbert, Tom Hilbert, Andéol G. Cadic-Melchior, Andéol G. Cadic-Melchior, Elena Beanato, Elena Beanato, Chang-Hyun Park, Chang-Hyun Park, Takuya Morishita, Takuya Morishita, Maximilian J. Wessel, Maximilian J. Wessel, Maximilian J. Wessel, Simona Schiavi, Simona Schiavi, Alessandro Daducci, Tobias Kober, Tobias Kober, Tobias Kober, Erick J. Canales-Rodríguez, Friedhelm C. Hummel, Friedhelm C. Hummel, Friedhelm C. Hummel, Jean-Philippe Thiran, Jean-Philippe Thiran, Jean-Philippe Thiran   +44 more
doaj   +1 more source

Laying foundations to quantify the "Effort of Reproducibility" [PDF]

arXiv, 2023
Why are some research studies easy to reproduce while others are difficult? Casting doubt on the accuracy of scientific work is not fruitful, especially when an individual researcher cannot reproduce the claims made in the paper. There could be many subjective reasons behind the inability to reproduce a scientific paper.
arxiv  

Registered report: Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

eLife, 2015
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers,
Brad Evans, Erin Griner, Reproducibility Project: Cancer Biology   +2 more
doaj   +1 more source