Results 41 to 50 of about 2,089,944 (391)

On Representation and Reproducibility [PDF]

open access: yesJournal of Cognitive Neuroscience, 2003
Two papers were selected this year for their implementation of novel analytical approaches on archived data provided by the Dartmouth fMRI Data Center. Coincidentally, the two independent studies, conducted in different parts of the world, tested their models on the same data set, originally collected by Ishai, Ungerleider, Martin, Schouten, and Haxby (
openaire   +3 more sources

Replication Study: Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

open access: yeseLife, 2018
As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Repass et al., 2016), that described how we intended to replicate an experiment from the paper ‘Fusobacterium nucleatum infection is prevalent in human colorectal ...
John Repass   +1 more
doaj   +1 more source

Reproducibility of lymphovascular space invasion (LVSI) assessment in endometrial cancer [PDF]

open access: yes, 2019
Aims Lymphovascular space invasion (LVSI) in endometrial cancer (EC) is an important prognostic variable impacting on a patient's individual recurrence risk and adjuvant treatment recommendations.
Bartosch, Carla   +11 more
core   +2 more sources

A RIGHT TO REPRODUCE? [PDF]

open access: yesBioethics, 2010
ABSTRACTHow should we conceive of a right to reproduce? And, morally speaking, what might be said to justify such a right? These are just two questions of interest that are raised by the technologies of assisted reproduction. This paper analyses the possible legitimate grounds for a right to reproduce within the two main theories of rights; interest ...
openaire   +5 more sources

RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays.

open access: yesGenome Research, 2008
Ultra-high-throughput sequencing is emerging as an attractive alternative to microarrays for genotyping, analysis of methylation patterns, and identification of transcription factor binding sites.
J. Marioni   +4 more
semanticscholar   +1 more source

Reproducibility in research [PDF]

open access: yesDisease Models & Mechanisms, 2011
Summary Progress in biomedical research depends in part on being able to build on the findings of other researchers – and thereby on being able to apply others’ methods to your own research. However, most of us have struggled to understand how to repeat or adapt another researcher’s study because of minimal or missing details in the ...
openaire   +4 more sources

Replication Study: The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

open access: yeseLife, 2017
In 2015, as part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Chroscinski et al., 2015) that described how we intended to replicate selected experiments from the paper “The CD47-signal regulatory protein alpha (SIRPa)
Stephen K Horrigan   +1 more
doaj   +1 more source

A theory and methodology to quantify knowledge [PDF]

open access: yesRoyal Society Open Science, 2019
This article proposes quantitative answers to meta-scientific questions including ‘how much knowledge is attained by a research field?’, ‘how rapidly is a field making progress?’, ‘what is the expected reproducibility of a result?’, ‘how much knowledge ...
Daniele Fanelli
doaj   +1 more source

The Polygenic Score Catalog: an open database for reproducibility and systematic evaluation

open access: yesmedRxiv, 2020
Polygenic [risk] scores (PGS) can enhance prediction and understanding of common diseases and traits. However, the reproducibility of PGS and their subsequent applications in biological and clinical research have been hindered by several factors ...
Samuel A. Lambert   +11 more
semanticscholar   +1 more source

Replication Study: Discovery and preclinical validation of drug indications using compendia of public gene expression data

open access: yeseLife, 2017
In 2015, as part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Kandela et al., 2015) that described how we intended to replicate selected experiments from the paper “Discovery and Preclinical Validation of Drug ...
Irawati Kandela   +2 more
doaj   +1 more source

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