Results 61 to 70 of about 1,263,629 (290)
In-ear EEG biometrics for feasible and readily collectable real-world person authentication
, 2017 The use of EEG as a biometrics modality has been investigated for about a decade, however its feasibility in real-world applications is not yet conclusively established, mainly due to the issues with collectability and reproducibility.
Goverdovsky, Valentin +2 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Reproducibility Performance Test of Multi Metal Oxide Catalyst in Selective Oxidation of Propane using Combinatorial Technology [PDF]
, 2014 The concept of rapid catalyst screening using combinatorial technology was applied in the development of selective oxidation catalyst. In this paper, the design, Design of Experiment (DOE) and catalytic results are discussed to demonstrate the ...
Abd Hamid, Sharifah Bee +1 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A theory and methodology to quantify knowledge [PDF]
Royal Society Open Science, 2019 This article proposes quantitative answers to meta-scientific questions including ‘how much knowledge is attained by a research field?’, ‘how rapidly is a field making progress?’, ‘what is the expected reproducibility of a result?’, ‘how much knowledge ...
Daniele Fanelli
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Unified Behavioral Scoring for Preclinical Models
Frontiers in Neuroscience, 2020 Preclinical mental health research relies upon animal models, and whilst many encouraging advances are being made, reproducibility and translational relevance may be limited by sub-optimal testing or model choices.
David J. Harrison +7 more
doaj +1 more source
Direct in-vial collection for liquid-scintillation assay of carbon-14 and tritium [PDF]
, 1969 Dissolution of biological materials combines the simplicity of oxygen-flask combustion with the reproducibility and purity of the final product, and convenience of direct in-vial collection of the sample by the sealed-tube method. It assures quantitative
Huebner, L. G., Kisieleski, W. E.
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source