Results 61 to 70 of about 1,534,989 (367)
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, EarlyView.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
Systematizing Effective Practice, Embedding It in Standard Practice
Patterns, 2020 Academia uses methods and techniques that are cutting edge and constantly evolving, while the underlying cultures and working practices remain rooted in the 19th-century model of the independent scientist.
The UK Reproducibility Network Steering Group
doaj
p-value based statistical significance tests: Concepts, misuses, critiques, solutions and beyond [PDF]
Computational Ecology and Software, 2022 The p-value is at the heart of statistical significance tests, a very important issue related to the role of statistical inference in advancing scientific discovery. Over the past few decades, p-value based statistical significance tests have been widely
WenJun Zhang
doaj
Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology
eLife, 2021 As part of the Reproducibility Project: Cancer Biology, we published Registered Reports that described how we intended to replicate selected experiments from 29 high-impact preclinical cancer biology papers published between 2010 and 2012.
Timothy M Errington +27 more
doaj +1 more source
The Costs of Reproducibility [PDF]
Neuron, 2019 Improving the reproducibility of neuroscience research is of great concern, especially to early-career researchers (ECRs). Here I outline the potential costs for ECRs in adopting practices to improve reproducibility. I highlight the ways in which ECRs can achieve their career goals while doing better science and the need for established researchers to ...
openaire +3 more sources
FEBS Letters, EarlyView.The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva +1 more
wiley +1 more source
IEEE Access, 2019 Data analytics processes such as scientific workflows tend to be executed repeatedly, with varying dependencies and input datasets. The case has been made in the past for tracking the provenance of the final information products through the workflow ...
Priyaa Thavasimani +2 more
doaj +1 more source
Investigating the replicability of preclinical cancer biology
eLife, 2021 Replicability is an important feature of scientific research, but aspects of contemporary research culture, such as an emphasis on novelty, can make replicability seem less important than it should be.
Timothy M Errington +6 more
doaj +1 more source
Variability and reproducibility in deep learning for medical image segmentation
Scientific Reports, 2020 Medical image segmentation is an important tool for current clinical applications. It is the backbone of numerous clinical diagnosis methods, oncological treatments and computer-integrated surgeries.
Félix Renard +3 more
semanticscholar +1 more source
Advocating for reproducibility
IASSIST Quarterly, 2020 As guest editors, we are excited to publish this special double issue of IASSIST Quarterly. The topics of reproducibility, replicability, and transparency have been addressed in past issues of IASSIST Quarterly and at the IASSIST conference, but this double issue is entirely focused on these issues. In recent years, efforts “to improve the ...
Dekker, Harrison, Riegelman, Amy
openaire +5 more sources