Results 121 to 130 of about 1,463,180 (385)

Reproducibility of AMPLICOR enterovirus PCR test results [PDF]

open access: yesJournal of Clinical Microbiology, 1997
The reproducibility of AMPLICOR enterovirus PCR test results was determined with clinical samples of cerebrospinal fluid, serum, urine, and throat and rectal swabs. Among 608 samples from which duplicate aliquots were run simultaneously, only seven pairs gave discordant results.
openaire   +3 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Updates to data versions and analytic methods influence the reproducibility of results from epigenome-wide association studies. [PDF]

open access: yesEpigenetics, 2022
Lussier AA   +8 more
europepmc   +1 more source

Generalizability and reproducibility of functional connectivity in autism

open access: yesMolecular Autism, 2019
BackgroundAutism is hypothesized to represent a disorder of brain connectivity, yet patterns of atypical functional connectivity show marked heterogeneity across individuals.MethodsWe used a large multi-site dataset comprised of a heterogeneous ...
J. King   +15 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Adaptação transcultural, confiabilidade e validade da escala de resiliência

open access: yesCadernos de Saúde Pública
Busca-se apresentar os resultados da adaptação transcultural para o português da escala de resilência de Wagnild & Young e da avaliação psicométrica desta.
Renata P. Pesce   +5 more
doaj  

Varieties of Sadistic Tendencies: adaptation and internal structure in Brazil [PDF]

open access: yesEstudos de Psicologia (Campinas)
Objective This study aims to present an adaptation and evidence of construct validity of the Varieties of Sadistic Tendencies for a sample in the Brazilian context. Method To this end, 260 participants from different states, with ages ranging from 18 to
Germano Gabriel Lima Esteves   +2 more
doaj   +1 more source

Publishing reproducible results supported by FAIR data

open access: yes, 2023
We discuss two techniques for processing and analysing data that at the same time generate the required metadata to create FAIR digital objects. These objects can then be published as supporting information for the results obtained. This approach requires minimum intervention from the researcher performing the processing and analysis tasks ...
openaire   +1 more source

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