Results 181 to 190 of about 1,417,965 (314)
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda+9 more
wiley +1 more source
Reproducibility of late gadolinium enhancement quantification techniques in ischemic and non-ischemic heart diseases (ReLate study). [PDF]
Gavrysh J+11 more
europepmc +1 more source
The Road Towards Reproducibility in Science: The Case of Data Citation [PDF]
Ferro, Nicola, Silvello, Gianmaria
core +1 more source
CD9‐association with PIP2 areas is regulated by a CD9 salt bridge
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi+2 more
wiley +1 more source
A metric of knowledge as information compression reflects reproducibility predictions for biomedical experiments. [PDF]
Fanelli D, Tan PB, Amaral OB, Neves K.
europepmc +1 more source
R code and radiocarbon dates to reproduce figures and results of our paper "Population dynamics ..."
Salvador Pardo-Gordó+1 more
openalex +2 more sources
Reproduce experiment results on Heavy-user Bias in A/B testing
Fisnik Berisha+2 more
openalex +2 more sources
Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno+12 more
wiley +1 more source