Results 51 to 60 of about 1,417,965 (314)

In Vitro Evaluation of Eslicarbazepine Delivery via Enteral Feeding Tubes [PDF]

, 2017
Purpose: The feasibility of preparing an eslicarbazepine acetate suspension using Aptiom tablets for administration via enteral feeding tubes was evaluated.
Dave, Vivek S, Hughes, Susan, Reindel, Kristin, Zhao, Fang   +3 more
core   +2 more sources

Reproducible Results Policy [PDF]

Journal of Water Resources Planning and Management, 2021
David E. Rosenberg, Amber Spackman Jones, Yves Filion, Rebecca Teasley, Samuel Sandoval-Solis, James H. Stagge, Adel Abdallah, Anthony Castronova, Avi Ostfeld, David Watkins   +9 more
openaire   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

A reproducible approach with R markdown to automatic classification of medical certificates in French [PDF]

, 2017
In this paper, we report the ongoing developments of our first participation to the Cross-Language Evaluation Forum (CLEF) eHealth Task 1: “Multilingual Information Extraction - ICD10 coding” (Névéol et al., 2017).
Beghini, Federica, Di Nunzio, Giorgio Maria, Henrot, Genevi\ue8ve, Vezzani, Federica   +3 more
core   +2 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Reproduce experimental results from a paper

, 2022
Reproduce experimental results from a paper: Do Channels Matter?
Ceranic, Amila, Dizdar, Riad, Sokoli, Albulena   +2 more
openaire   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

HiCRep: assessing the reproducibility of Hi-C data using a stratum-adjusted correlation coefficient

bioRxiv, 2017
Hi-C is a powerful technology for studying genome-wide chromatin interactions. However, current methods for assessing Hi-C data reproducibility can produce misleading results because they ignore spatial features in Hi-C data, such as domain structure and
Tao Yang, Feipeng Zhang, G. Yardımcı, R. Hardison, William Stafford Noble, Feng Yue, Qunhua Li   +6 more
semanticscholar   +1 more source