Results 71 to 80 of about 166,851,649 (309)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Validity of content and face validity of the instrument "Perception of behaviors of harmonized care" Validez de contenido y validez facial del instrumento "Percepción de comportamientos de cuidado humanizado" Validade de conteúdo e validade facial do instrumento "Percepção de comportamentos de cuidado humanizado"

open access: yesAvances en Enfermería, 2008
A methodological research was carried out whose objective was to determine the face validity and content validity of the instrument "Perception of behaviors of humanized nursing care" of Rivera and Triana, with twelve patients and/or their permanent care
VARGAS ROSERO ELIZABETH   +1 more
doaj  

Comparison of the Size Measurement of Gallbladder Polyps by Three Different Radiologists in Abdominal Ultrasonography

open access: yesTomography
Background: There is little information regarding the size measurement differences in gallbladder (GB) polyps performed by different radiologists on abdominal ultrasonography (US). Aim: To reveal the differences in GB polyp size measurements performed by
Kyu-Chong Lee   +2 more
doaj   +1 more source

Reproducible Results Policy [PDF]

open access: yesJournal of Water Resources Planning and Management, 2021
David E. Rosenberg   +9 more
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Design and psychometric evaluation of nurses’ social health tool

open access: yesJournal of Education and Health Promotion
BACKGROUND: Given the impact of nurses’ social health on the quality of care, its evaluation is essential. To evaluate social health, we need a specific and appropriate tool.
Leila Ghanbari-Afra   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Research Reproducibility 2016 - Speakers

open access: yes, 2016
2016 Research Reproducibility Conference ...

core  

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