Results 71 to 80 of about 1,138,858 (299)

Validity and reliability of fluoroscopy for digital radiography: a new way to evaluate diaphragmatic mobility

open access: yesBMC Pulmonary Medicine, 2017
Background Fluoroscopy is considered the most accurate method to evaluate the diaphragm, yet most existing methods for measuring diaphragmatic mobility using fluoroscopy are complex.
Bruna Estima Leal   +6 more
doaj   +1 more source

Self-Estimated Functional Inability because of Pain questionnaire for Brazilian workers with musculoskeletal pain: face and content validity

open access: yesFisioterapia e Pesquisa, 2021
Our study aimed to perform the face and content validity of Self-Estimated Functional Inability because of Pain (SEFIP) for workers, here called the SEFIP-work questionnaire. This is a questionnaire validity study.
Cezar Augusto Brito Pinheiro   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Improving transparency and scientific rigor in academic publishing. [PDF]

open access: yes, 2018
Progress in basic and clinical research is slowed when researchers fail to provide a complete and accurate report of how a study was designed, executed, and the results analyzed.
Alberts   +94 more
core   +3 more sources

Surface Electromyographic Assessment of Swallowing Function

open access: yesIranian Journal of Medical Sciences, 2017
The reliability of surface electromyographic (sEMG) variables during swallowing determines the potential usefulness of these measures in swallowing assessment and treatment.
Marziyeh Poorjavad   +3 more
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The development of a scale of the Guttman Type for the assessment of mobility disability in multiple sclerosis [PDF]

open access: yes, 1999
Objective: The aim of the study was to develop a valid and reliable unidimensional scale of the Guttman type for the assessment of mobility disability in multiple sclerosis (MS).
De Souza, LH
core   +1 more source

RELIABILITY OF A NEW BAROPODOMETRY PLATFORM DURING BAREFOOT WALKING IN HEALTHY ADULTS [PDF]

open access: yesActa Ortopédica Brasileira
Objective: To expand existing knowledge on gait parameters in a healthy population using a baropodometer and to ensure the reliability of the equipment.
Silvia Iovine Kobata   +3 more
doaj   +1 more source

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