Results 71 to 80 of about 4,106,574 (383)

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Reproducibility and construct validity of three non-invasive instruments for assessing the trunk range of motion in patients with low back pain

open access: yesFisioterapia e Pesquisa, 2014
Although there is a wide variety of methods and instruments aiming to assess the trunk range of motion, there is uncertainty regarding their construct validity and reproducibility.
Gabrielle Zoldan Ganzalez   +5 more
doaj   +2 more sources

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Surface Electromyographic Assessment of Swallowing Function

open access: yesIranian Journal of Medical Sciences, 2017
The reliability of surface electromyographic (sEMG) variables during swallowing determines the potential usefulness of these measures in swallowing assessment and treatment.
Marziyeh Poorjavad   +3 more
doaj  

An analysis of key indicators of reproducibility in radiology

open access: yesInsights into Imaging, 2020
Background Given the central role of radiology in patient care, it is important that radiological research is grounded in reproducible science. It is unclear whether there is a lack of reproducibility or transparency in radiologic research.
Bryan D. Wright   +6 more
doaj   +1 more source

Inter-observer variation in two-dimensional and three-dimensional ultrasound measurement of papillary thyroid microcarcinoma

open access: yesCancer Imaging, 2023
Backgrounds The reliable ultrasound (US) measurements of papillary thyroid microcarcinoma (PTMC) are very important during active surveillance. This prospective study was design to investigate the inter-observer reliability and agreement of two ...
Lin Yan   +3 more
doaj   +1 more source

Reproducibility Requires Consolidated Artifacts [PDF]

open access: yesarXiv, 2023
Machine learning is facing a 'reproducibility crisis' where a significant number of works report failures when attempting to reproduce previously published results. We evaluate the sources of reproducibility failures using a meta-analysis of 142 replication studies from ReScience C and 204 code repositories. We find that missing experiment details such
arxiv  

Use of Microtome Sections to Determine the Effect of Retention Aid on Filler Distribution [PDF]

open access: yes, 1964
Two-sidedness of paper is an all too common problem in the paper industry. Most of the undesirable results are due to the uneven distribution of filler in the sheet.
Farrand, James
core   +1 more source

Optical coherence tomography fast versus regular macular thickness mapping in diabetic retinopathy [PDF]

open access: yes, 2008
Objective: The purpose of the study was to investigate if absolute values and reproducibility of thickness maps obtained from 2 optical coherence tomography (OCT) scanning protocols, regular high-resolution and fast low-density mode, differ in patients ...
Ceklic, Lala   +2 more
core   +1 more source

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