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Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology. [PDF]
As part of the Reproducibility Project: Cancer Biology, we published Registered Reports that described how we intended to replicate selected experiments from 29 high-impact preclinical cancer biology papers published between 2010 and 2012. Replication experiments were completed and Replication Studies reporting the results were submitted for 18 papers,
Errington TM+27 more
europepmc +6 more sources
Unique Identification of research resources in studies in Reproducibility Project: Cancer Biology
Nicole Vasilevsky+4 more
semanticscholar +4 more sources
Investigating the replicability of preclinical cancer biology
Replicability is an important feature of scientific research, but aspects of contemporary research culture, such as an emphasis on novelty, can make replicability seem less important than it should be.
Timothy M. Errington+6 more
semanticscholar +1 more source
Challenges for assessing replicability in preclinical cancer biology
We conducted the Reproducibility Project: Cancer Biology to investigate the replicability of preclinical research in cancer biology. The initial aim of the project was to repeat 193 experiments from 53 high-impact papers, using an approach in which the ...
Timothy M. Errington+4 more
semanticscholar +1 more source
Is preclinical research in cancer biology reproducible enough?
The Reproducibility Project: Cancer Biology (RPCB) was established to provide evidence about reproducibility in basic and preclinical cancer research, and to identify the factors that influence reproducibility more generally.
P. Kane, J. Kimmelman
semanticscholar +1 more source
The Replication of Equivalence Studies [PDF]
Replication studies are increasingly conducted to assess the credibility of scientific findings. Most of these replication attempts target studies with a superiority design, but there is a lack of methodology regarding the analysis of replication studies
Charlotte Micheloud, Leonhard Held
semanticscholar +1 more source
Replication of"null results"-- Absence of evidence or evidence of absence? [PDF]
In several large-scale replication projects, statistically non-significant results in both the original and the replication study have been interpreted as a"replication success".
Samuel Pawel+3 more
semanticscholar +1 more source