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Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology. [PDF]

open access: goldElife, 2021
As part of the Reproducibility Project: Cancer Biology, we published Registered Reports that described how we intended to replicate selected experiments from 29 high-impact preclinical cancer biology papers published between 2010 and 2012. Replication experiments were completed and Replication Studies reporting the results were submitted for 18 papers,
Errington TM   +27 more
europepmc   +6 more sources

Author response: Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology

open access: gold, 2021
Timothy M. Errington   +27 more
semanticscholar   +3 more sources

Investigating the replicability of preclinical cancer biology

open access: yeseLife, 2021
Replicability is an important feature of scientific research, but aspects of contemporary research culture, such as an emphasis on novelty, can make replicability seem less important than it should be.
Timothy M. Errington   +6 more
semanticscholar   +1 more source

Challenges for assessing replicability in preclinical cancer biology

open access: yeseLife, 2021
We conducted the Reproducibility Project: Cancer Biology to investigate the replicability of preclinical research in cancer biology. The initial aim of the project was to repeat 193 experiments from 53 high-impact papers, using an approach in which the ...
Timothy M. Errington   +4 more
semanticscholar   +1 more source

Is preclinical research in cancer biology reproducible enough?

open access: yeseLife, 2021
The Reproducibility Project: Cancer Biology (RPCB) was established to provide evidence about reproducibility in basic and preclinical cancer research, and to identify the factors that influence reproducibility more generally.
P. Kane, J. Kimmelman
semanticscholar   +1 more source

The Replication of Equivalence Studies [PDF]

open access: yesBiometrical journal. Biometrische Zeitschrift, 2022
Replication studies are increasingly conducted to assess the credibility of scientific findings. Most of these replication attempts target studies with a superiority design, but there is a lack of methodology regarding the analysis of replication studies
Charlotte Micheloud, Leonhard Held
semanticscholar   +1 more source

Replication of"null results"-- Absence of evidence or evidence of absence? [PDF]

open access: yes, 2023
In several large-scale replication projects, statistically non-significant results in both the original and the replication study have been interpreted as a"replication success".
Samuel Pawel   +3 more
semanticscholar   +1 more source

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