Results 11 to 20 of about 115,296 (125)
Reproducible research using biomodels [PDF]
Bulletin of Mathematical Biology 80:3081-3087 (2018), 2018 Like other types of computational research, modeling and simulation of biological processes (biomodels) is still largely communicated without sufficient detail to allow independent reproduction of results. But reproducibility in this area of research could easily be achieved by making use of existing resources, such as supplying models in standard ...
arxiv +1 more source
An open investigation of the reproducibility of cancer biology research
eLife, 2014 It is widely believed that research that builds upon previously published findings has reproduced the original work. However, it is rare for researchers to perform or publish direct replications of existing results.
Timothy M. Errington +5 more
semanticscholar +1 more source
eLife, 2020 As part of the Reproducibility Project: Cancer Biology we published a Registered Report (Khan et al., 2015), that described how we intended to replicate selected experiments from the paper "A coding-independent function of gene and pseudogene mRNAs ...
J. Kerwin +6 more
semanticscholar +1 more source
Practical Resources for Enhancing the Reproducibility of Mechanistic Modeling in Systems Biology [PDF]
arXiv, 2021 Although reproducibility is a core tenet of the scientific method, it remains challenging to reproduce many results. Surprisingly, this also holds true for computational results in domains such as systems biology where there have been extensive standardization efforts. For example, Tiwari et al.
arxiv
eLife, 2021 As the final outputs of the Reproducibility Project: Cancer Biology are published, it is clear that preclinical research in cancer biology is not as reproducible as it should be.
Peter Rodgers, Andy Collings
semanticscholar +1 more source
The Biological Data Sustainability Paradox [PDF]
arXiv, 2023 Biological data in digital form has become a, if not the, driving force behind innovations in biology, medicine, and the environment. No study and no model would be complete without access to digital data (including text) collected by others and available in public repositories.
arxiv
Clinical Chemistry, 2017 The recent publication of first results from the “Reproducibility Project: Cancer Biology” has stirred debate. The project synopsis put together by Nosek and Errington (1) tried to describe carefully what replication means, how to judge whether “same ...
J. Ioannidis
semanticscholar +1 more source
eLife, 2017 In 2015, as part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Kandela et al., 2015) that described how we intended to replicate selected experiments from the paper “Coadministration of a tumor-penetrating peptide ...
Christine Mantis +3 more
semanticscholar +1 more source
Replication Study: Systematic identification of genomic markers of drug sensitivity in cancer cells
eLife, 2018 In 2016, as part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Vanden Heuvel et al., 2016), that described how we intended to replicate selected experiments from the paper ‘Systematic identification of genomic markers ...
J. V. Vanden Heuvel +7 more
semanticscholar +1 more source
Can cancer researchers accurately judge whether preclinical reports will reproduce?
PLoS Biology, 2017 There is vigorous debate about the reproducibility of research findings in cancer biology. Whether scientists can accurately assess which experiments will reproduce original findings is important to determining the pace at which science self-corrects. We
Daniel Benjamin, D. Mandel, J. Kimmelman
semanticscholar +1 more source