Results 21 to 30 of about 115,296 (125)

Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions

open access: yesGenome Biology, 2021
Background Targeted sequencing using oncopanels requires comprehensive assessments of accuracy and detection sensitivity to ensure analytical validity. By employing reference materials characterized by the U.S.
Binsheng Gong   +150 more
semanticscholar   +1 more source

Reproducibility in machine learning for medical imaging [PDF]

open access: yesarXiv, 2022
Reproducibility is a cornerstone of science, as the replication of findings is the process through which they become knowledge. It is widely considered that many fields of science are undergoing a reproducibility crisis. This has led to the publications of various guidelines in order to improve research reproducibility.
arxiv  

If your P value looks too good to be true, it probably is: Communicating reproducibility and variability in cell biology [PDF]

open access: yesJ. Cell. Biol. 219 (2020) e202001064, 2019
The cell biology literature is littered with erroneously tiny P values, often the result of evaluating individual cells as independent samples. Because readers use P values and error bars to infer whether a reported difference would likely recur if the experiment were repeated, the sample size N used for statistical tests should actually be the number ...
arxiv   +1 more source

Registered report: the microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

open access: yeseLife, 2015
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers,
Jia Li   +2 more
semanticscholar   +1 more source

Registered report: A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

open access: yeseLife, 2016
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a substantial number of high-profile papers in the field of cancer biology.
Babette Haven   +6 more
semanticscholar   +1 more source

The Practice of Ensuring Repeatable and Reproducible Computational Models [PDF]

open access: yesarXiv, 2021
Recent studies have shown that the majority of published computational models in systems biology and physiology are not repeatable or reproducible. There are a variety of reasons for this. One of the most likely reasons is that given how busy modern researchers are and the fact that no credit is given to authors for publishing repeatable work, it is ...
arxiv  

Registered report: Intestinal inflammation targets cancer-inducing activity of the microbiota

open access: yeseLife, 2015
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
Kate Eaton   +6 more
semanticscholar   +1 more source

Heterogeneity of cells may explain allometric scaling of metabolic rate [PDF]

open access: yesBiosystems 130, 11-16 (2015), 2015
The origin of allometric scaling of metabolic rate is a long-standing question in biology. Several models have been proposed for explaining the origin; however, they have advantages and disadvantages. In particular, previous models only demonstrate either two important observations for the allometric scaling: the variability of scaling exponents and ...
arxiv   +1 more source

Registered Report: COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

open access: yeseLife, 2016
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers,
Vidhu Sharma   +4 more
semanticscholar   +1 more source

Registered report: Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

open access: yeseLife, 2015
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
S. Raouf   +7 more
semanticscholar   +1 more source

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