Results 31 to 40 of about 115,296 (125)
Recommendations to enhance rigor and reproducibility in biomedical research [PDF]
arXiv, 2020 Computational methods have reshaped the landscape of modern biology. While the biomedical community is increasingly dependent on computational tools, the mechanisms ensuring open data, open software, and reproducibility are variably enforced by academic institutions, funders, and publishers.
arxiv
Asking Biological Questions of Physical Systems: the Device Approach to Emergent Properties [PDF]
Journal of Molecular Liquids (2018) 270: 212-217, 2018 Life occurs in concentrated `Ringer Solutions' derived from seawater that Lesser Blum studied for most of his life. As we worked together, Lesser and I realized that the questions asked of those solutions were quite different in biology from those in the physical chemistry he knew. Biology is inherited. Information is passed by handfuls of atoms in the
arxiv +1 more source
eLife, 2019 As part of the Reproducibility Project: Cancer Biology we published a Registered Report (Evans et al., 2015), that described how we intended to replicate selected experiments from the paper ‘Wnt activity defines colon cancer stem cells and is regulated ...
Anthony Essex +9 more
semanticscholar +1 more source
eLife, 2019 As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Li et al., 2015), that described how we intended to replicate selected experiments from the paper ‘The microRNA miR-34a inhibits prostate cancer stem cells and ...
Xuefei Yan +9 more
semanticscholar +1 more source
Registered report: Systematic identification of genomic markers of drug sensitivity in cancer cells
eLife, 2016 The Reproducibility Project: Cancer Biology seeks to address growing concerns about the reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology.
J. V. Vanden Heuvel +2 more
semanticscholar +1 more source
Statistical mechanics of warm and cold unfolding in proteins [PDF]
, 1997 We present a statistical mechanics treatment of the stability of globular proteins which takes explicitly into account the coupling between the protein and water degrees of freedom. This allows us to describe both the cold and the warm unfolding, thus qualitatively reproducing the known thermodynamics of proteins.
arxiv +1 more source
Origin of life from a maker's perspective -- focus on protocellular compartments in bottom-up synthetic biology [PDF]
arXiv, 2022 The origin of life is shrouded in mystery, with few surviving clues, obscured by evolutionary competition. Previous reviews have touched on the complementary approaches of top-down and bottom-up synthetic biology to augment our understanding of living systems.
arxiv
eLife, 2015 The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by replicating selected results from a substantial number of high-profile papers in the field of cancer biology.
James A. Evans +6 more
semanticscholar +1 more source
ProBio: A Protocol-guided Multimodal Dataset for Molecular Biology Lab [PDF]
arXiv, 2023 The challenge of replicating research results has posed a significant impediment to the field of molecular biology. The advent of modern intelligent systems has led to notable progress in various domains. Consequently, we embarked on an investigation of intelligent monitoring systems as a means of tackling the issue of the reproducibility crisis ...
arxiv
eLife, 2015 The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by replicating selected results from a substantial number of high-profile papers in the field of cancer biology published between ...
F. Incardona +6 more
semanticscholar +1 more source