Results 111 to 120 of about 418,446 (282)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

CUF-Links: Continuous and Ubiquitous FAIRness Linkages for reproducible research. [PDF]

Computer (Long Beach Calif), 2022
Foster I, Kesselman C.
europepmc   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Towards reproducible research in recurrent pregnancy loss immunology: Learning from cancer microenvironment deconvolution. [PDF]

Front Immunol, 2023
Betti M, Vizza E, Piccione E, Pietropolli A, Chiofalo B, Pallocca M, Bruno V.   +6 more
europepmc   +1 more source

Reproducible Research in Pattern Recognition

, 2021
Bertrand Kerautret, Miguel Colom, Adrien Krähenbühl, Daniel Lopresti, Pascal Monasse, Hugues Talbot   +5 more
openalex   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Towards standardized and reproducible research in skin microbiomes. [PDF]

Environ Microbiol, 2022
Ruuskanen MO, Vats D, Potbhare R, RaviKumar A, Munukka E, Ashma R, Lahti L.   +6 more
europepmc   +1 more source

Results of the ISMRM 2020 joint Reproducible Research & Quantitative MR study groups reproducibility challenge on phantom and human brain T₁ mapping

, 2023
Mathieu Boudreau, Agâh Karakuzu, Julien Cohen‐Adad, Ecem Bozkurt, Madeline Carr, Marco Castellaro, Luis Concha, Mariya Doneva, Seraina A. Dual, Alex Ensworth, Alexandru Foias, Véronique Fortier, Refaat E. Gabr, Guillaume Gilbert, Carri Glide‐Hurst, Matthew Grech‐Sollars, Siyuan Hu, Oscar Jalnefjord, Jorge Jovicich, Kübra Keskin, Peter Koken, Anastasia Kolokotronis, Simran Kukran, Nam G. Lee, Ives R. Levesque, Bochao Li, Dan Ma, Burkhard Mädler, Nyasha G. Maforo, Jamie Near, Erick H. Pasaye, Alonso Ramírez-Manzanares, Ben Statton, Christian Stehning, Stefano Tambalo, Ye Tian, Chenyang Wang, Kilian Weis, Niloufar Zakariaei, Shuo Zhang, Ziwei Zhao, Nikola Stikov   +41 more
openalex   +1 more source

Rigor and reproducibility training for first year medical students in research pathways [PDF]

, 2020
Kate L. Lapane, Catherine Dubé
openalex   +1 more source

Open Science and Research Reproducibility

ecancermedicalscience, 2016
Many scientists, journals and funders are concerned about the low reproducibility of many scientific findings. One approach that may serve to improve the reliability and robustness of research is open science. Here I argue that the process of pre-registering study protocols, sharing study materials and data, and posting preprints of manuscripts may ...
openaire   +4 more sources