Results 81 to 90 of about 4,209,277 (404)

Depletion and social reproduction [PDF]

, 2011
Much work has been done on the unaccounted contribution of social reproductive work to national economies. What has been less studied is the consequence of this neglect for individuals, households and communities engaged in social reproduction.
Hoskyns, Catherine, Rai, Shirin, Thomas, Dania   +2 more
core  

The Work of Art in the Age of Mechanical Reproduction

, 2016
Despite its relative brevity, Walter Benjamin’s essay “The Work of Art in the Age of Mechanical Reproduction,” continues to inspire significant scholarly attention as a major work in the history of modern aesthetic and political criticism.
Anthony Wallace
semanticscholar   +1 more source

Genomic analyses of primitive, wild and cultivated citrus provide insights into asexual reproduction

Nature Genetics, 2017
The emergence of apomixis—the transition from sexual to asexual reproduction—is a prominent feature of modern citrus. Here we de novo sequenced and comprehensively studied the genomes of four representative citrus species.
Xia Wang, Yuantao Xu, Siqi Zhang, Li Cao, Yue Huang, Jun-Feng Cheng, Guizhi Wu, S. Tian, Chunli Chen, Yan Liu, Huiwen Yu, Xiaoming Yang, H. Lan, Nannan Wang, Lun Wang, Jidi Xu, Xiaolin Jiang, Zongzhou Xie, M. Tan, R. Larkin, Lingling Chen, Bin-Guang Ma, Y. Ruan, X. Deng, Qiang Xu   +24 more
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Measurability of the epidemic reproduction number in data-driven contact networks

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance The analysis of real epidemiological data has raised issues of the adequacy of the classic homogeneous modeling framework and quantities, such as the basic reproduction number in real-world situations.
Quan-Hui Liu, M. Ajelli, A. Aleta, S. Merler, Y. Moreno, Alessandro Vespignani   +5 more
semanticscholar   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Reproduction-Immunity Trade-Offs in Insects.

Annual Review of Entomology, 2016
Immune defense and reproduction are physiologically and energetically demanding processes and have been observed to trade off in a diversity of female insects.
Robin A. Schwenke, B. Lazzaro, M. Wolfner   +2 more
semanticscholar   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source