Results 91 to 100 of about 5,005,502 (303)

Proposed alternations to shop at 357 Glenhuntly Rd., Elsternwick : sections, ceiling & roof plans

, 1989
Commercial; shop; alternations to existing premisesPhysical format : thick stock paper; 845x600mmIncludes section and planMichael Factor, architect ; Drawn MFScale: 1:1001 ...
Factor, Michael
core  

Reproduction in a polluted world: implications for wildlife

, 2020
Environmental pollution is an increasing problem for wildlife globally. Animals are confronted with many different forms of pollution, including chemicals, light, noise, and heat, and these can disrupt critical biological processes such as reproduction ...
Bertram, Michael,, Sveriges lantbruksuniversitet., Brodin, Tomas,   +2 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Endometrial claudin-4 and leukemia inhibitory factor are associated with assisted reproduction outcome

Reproductive Biology and Endocrinology, 2009
Background Claudin-4 (CLDN4) is one of several proteins that act as molecular mediators of embryo implantation. Recently, we examined immunolabeling of leukemia inhibitory factor (LIF) in the endometrial tissue of 52 IVF patients, and found that LIF ...
Motta Eduardo LA, Smith Gary D, Silva Ismael DCG, Serafini Paulo C, Rocha André M, Baracat Edmund C   +5 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Transcription factor-dependent regulatory networks of sexual reproduction in Fusarium graminearum

mBio
Transcription factors (TFs) involved in sexual reproduction in filamentous fungi have been characterized. However, we have little understanding of how these TFs synergize within regulatory networks resulting in sexual development.
Wonyong Kim, Da-Woon Kim, Zheng Wang, Meng Liu, Jeffrey P. Townsend, Frances Trail   +5 more
doaj   +1 more source

Identifying environmental factors harmful to reproduction.

Environmental Health Perspectives, 1993
Reproduction is essential for the continuation of the species and for life itself. In biological terms, living and reproducing are essentially one and the same. There is, therefore, no sharp division between identifying factors harmful to reproduction and identifying factors harmful to life or vice versa.
openaire   +2 more sources

Alternations to shop at 357 Glenhuntly Rd., Elsternwick

, 1989
Commercial; shop; alternations to existing premisesPhysical format : thick stock paper; 845x600mmIncludes plan and elevationsMichael Factor, architectScale: 1 ...
Factor, Michael
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Economic Innovation as a Factor in Property Reproduction (Part 1)

Экономика и управление, 2019
The Russian economy has fallen behind in terms of technological development, despite numerous programs and strategies, as well as because priorities for innovative development, emphasized by the Russian government long ago, are now less evident.
Guzel’ F. Biglova, Oleg G. Smeshko
doaj