Results 121 to 130 of about 948,228 (268)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
National Journal of Community Medicine, 2019 Introduction: Globally ‘quality health care’ and particularly the domain of Reproductive and Child Health (RCH) services attract substantial attention. United Nations Population Fund (UNFPA) implemented Quality Assurance in Reproductive and Child Health
Prakash P Doke, Abhijit R Khanvilkar
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Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Applying Gender Action Plan Lessons: A Three-Year Road Map for Gender Mainstreaming (2011- 2013) [PDF]
, 2010 This transition plan identifies key lessons from the implementation of the World Bank Group action plan, Gender Equality as Smart Economics (GAP), and sets out a proposal to improve the performance on Gender and Development.
core
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Eelgrass Distribution in the Great Bay Estuary for 2011 [PDF]
, 2012 Eelgrass in the Great Bay Estuary declined in both distribution and biomass between 2010 and 2011. In 2011, eelgrass was once again mainly present in the Great Bay itself with limited distribution in Portsmouth Harbor and Little Bay.
Short, Frederick T.
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
The empowerment of pregnant women in Tonekabon, Iran
Caspian Journal of Reproductive Medicine, 2016 Background: Pregnant women empowerment is viewed by policy makers and health care practitioners as a mechanism to help pregnant women adapt to physical and psychological changes after pregnancy, and gain a satisfactory experience of childbirth.
Leila Hajipour +4 more
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