Results 111 to 120 of about 290,067 (258)

ASTROREPOMICS: A curated transcriptomic database for reproductive biology in space. [PDF]

iScience
Lung CF, Lin KI, Hsu YC.
europepmc   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Stem cell-based embryo models as a tool for reproductive biology. [PDF]

Mol Hum Reprod
Martinez Arias A, Dias A, Inamdar M.
europepmc   +1 more source

Reproductive biology: A genetic recipe for parthenogenesis. [PDF]

Curr Biol, 2023
Thomalla JM, Wolfner MF.
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Reproductive biology and anatomy of ammonites. [PDF]

Sci Rep
Klug C, Schweigert G, Lauer R, Lauer B, Fuchs D, Terakado K, Tajika A.   +6 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Reproductive Biology and Germination Ecology of <i>Phytolacca acinosa</i> in Its Secondary Range. [PDF]

Plants (Basel)
Stogova AV, Ivanovskii AA, Tkacheva EV, Zueva MA, Mamontov AK, Vinogradova YK, Shelepova OV.   +6 more
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Genetic variants in HELB contribute to premature ovarian insufficiency and early age of natural menopause

JCI Insight
Premature ovarian insufficiency (POI) is a complex reproductive disorder with a strong genetic component. The known POI causative genes currently account for only a small fraction of cases.
Yuncheng Pan, Yuexin Yu, Jitong Mo, Shuting Ren, Zixue Zhou, Xi Yang, Yiqing Liu, Feng Zhang, Yanqin You, Xiaojin Zhang, Yanhua Wu   +10 more
doaj   +1 more source