Results 91 to 100 of about 2,335,827 (339)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Hyaluronan control of the primary vascular barrier during early mouse pregnancy is mediated by uterine NK cells

open access: yesJCI Insight, 2020
Successful implantation is associated with a unique spatial pattern of vascular remodeling, characterized by profound peripheral neovascularization surrounding a periembryo avascular niche.
Ron Hadas   +11 more
doaj   +1 more source

Does Mother Nature Punish Rotten Kids? [PDF]

open access: yes
This paper studies the evolutionary game theory of parent-offspring conflict. It revisits a question posed by Gary Becker in economics and Richard Alexander in biology, namely "when do children act in accord with the reproductive interests of their ...
Carl Bergstrom, Ted Bergstrom
core  

Reproductive Biology of Silurid Catfishes Ompok Miostoma (Vaillant 1902) in Mahakam River East Kalimantan [PDF]

open access: yes, 2019
Biologi reproduksi ikan lais O. miostoma (Vaillant 1902)sebagai salah satu spesies endemik di Sungai Mahakam Kalimantan Timur belum pernah diketahui. Tujuan penelitian ini adalah menganalisisaspek reproduksi ikan laisberkaitan dengan Perubahan musimyang ...
Affandi, R. (Ridwan)   +4 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Elevated CCL2 causes Leydig cell malfunction in metabolic syndrome

open access: yesJCI Insight, 2020
Metabolic syndrome (MetS), which is associated with chronic inflammation, predisposes males to hypogonadism and subfertility. The underlying mechanism of these pathologies remains poorly understood.
Qingkui Jiang   +12 more
doaj   +1 more source

Reproductive biology of penaeid prawns [PDF]

open access: yes, 1983
In the contemporary period, knowledge of different aspects of reproduction in penaeid prawns is increasingly applied to improve their capture and culture fisheries.
Rao, P Vedavyasa
core  

Response of xenografts of developing human female reproductive tracts to the synthetic estrogen, diethylstilbestrol. [PDF]

open access: yes, 2017
Human female fetal reproductive tracts 9.5-22 weeks of gestation were grown for 1 month in ovariectomized athymic adult female mouse hosts that were either untreated or treated continuously with diethylstilbestrol (DES) via subcutaneous pellet.
Baskin, Laurence   +5 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The Reproductive Value in Distributed Optimal Control Models [PDF]

open access: yes
We show that in a large class of distributed optimal control models (DOCM), where population is described by a McKendrick type equation with an endogenous number of newborns, the reproductive value of Fisher shows up as part of the shadow price of the ...
Alexia Prskawetz   +3 more
core  

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