Results 71 to 80 of about 2,140,003 (260)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Management, Resources and Reproductive Biology [PDF]
Journal of Systemics, Cybernetics and Informatics, 2014 This work presents a relationship between environmental conditions and reproductive performance in modern humans. Birth rates and sex ratio (SRB) at birth were analyzed from large data scales.
Bernard Wallner, Martin Fieder
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
JCI Insight, 2023 Uterine leiomyomas cause heavy menstrual bleeding, anemia, and pregnancy loss in millions of women worldwide. Driver mutations in the transcriptional mediator complex subunit 12 (MED12) gene in uterine myometrial cells initiate 70% of leiomyomas that ...
Azna Zuberi +14 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Individual variation in reproductive success in the wandering Albatross [PDF]
, 2011 To conserve threatened species it is important to protect the productive individuals, and so I aimed to identify factors accounting for individual-level variation in long-term reproductive success.
Jones, M Genevieve W
core +1 more source
Increased hepatic glucose production with lower oxidative metabolism in the growth-restricted fetus
JCI InsightFetal growth restriction (FGR) is accompanied by early activation of hepatic glucose production (HGP), a hallmark of type 2 diabetes (T2D). Here, we used fetal hepatic catheterization to directly measure HGP and substrate flux in a sheep FGR model.
Laura D. Brown +6 more
doaj +1 more source
JCI Insight, 2023 Maternal decidual CD8+ T cells must integrate the antithetical demands of providing immunity to infection while maintaining immune tolerance for fetal and placental antigens.
Shweta Mahajan +9 more
doaj +1 more source
Responding to environmental change: plastic responses vary little in a colonial breeder [PDF]
, 2006 The impact of environmental change on animal populations is strongly influenced by the ability of individuals to plastically adjust key life-history events.
Cunningham, Emma J. A. +5 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source