Results 61 to 70 of about 2,335,827 (339)

Emerging issues and methodological advances in fisheries reproductive biology [PDF]

open access: yes, 2011
Although incorporating detailed reproductive data into all stock assessments is not a practical goal, the need to understand how reproductive biology affects population productivity is being increasingly recognized.More research focused on reproductive ...
Brown-Peterson, Nancy J.   +5 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Fidgetin-like 2 negatively regulates axonal growth and can be targeted to promote functional nerve regeneration

open access: yesJCI Insight, 2021
The microtubule (MT) cytoskeleton plays a critical role in axon growth and guidance. Here, we identify the MT-severing enzyme fidgetin-like 2 (FL2) as a negative regulator of axon regeneration and a therapeutic target for promoting nerve regeneration ...
Lisa Baker   +9 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

Spatiotemporal regulation of human IFN-ε and innate immunity in the female reproductive tract

open access: yesJCI Insight, 2022
Although published studies have demonstrated that IFN-ε has a crucial role in regulating protective immunity in the mouse female reproductive tract, expression and regulation of IFN-ε in the human female reproductive tract (hFRT) have not been ...
Nollaig M. Bourke   +11 more
doaj   +1 more source

ISOMETRY OF EGG SIZE IN A TEXAS POPULATION OF THE TURTLE STERNOTHERUS ODORATUS THAT EXHIBITS A NEARLY FIXED CLUTCH SIZE [PDF]

open access: yes, 2020
In evaluating optimal egg-size theory and the effects of anatomical constraints on egg size in turtles, pivotal questions concern the significance of the relationship of egg size to female body size and whether the relationship is isometric or ...
Lindeman, Peter V.
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Adverse outcomes in SARS-CoV-2–infected pregnant mice are gestational age–dependent and resolve with antiviral treatment

open access: yesThe Journal of Clinical Investigation, 2023
SARS-CoV-2 infection during pregnancy is associated with severe COVID-19 and adverse fetal outcomes, but the underlying mechanisms remain poorly understood. Moreover, clinical studies assessing therapeutics against SARS-CoV-2 in pregnancy are limited. To
Patrick S. Creisher   +12 more
doaj   +1 more source

Reproductive Biology of Largehead Hairtails, Trichiurus Lepturus Linnaeus, 1758 in the Coastal Area of Bantul Regency [PDF]

open access: yes, 2017
Ikan layur (Trichiurus lepturus) merupakan salah satu komoditas hasil tangkapan ikan di Daerah Istimewa Yogyakarta dengan jumlah produksi dan nilai yang tinggi.
Djumanto, D. (Djumanto)   +3 more
core  

Evo-devo of human adolescence: beyond disease models of early puberty [PDF]

open access: yes, 2013
Despite substantial heritability in pubertal development, much variation remains to be explained, leaving room for the influence of environmental factors to adjust its phenotypic trajectory in the service of fitness goals.
A Templeton   +69 more
core   +2 more sources

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