Results 81 to 90 of about 2,335,827 (339)

Increased hepatic glucose production with lower oxidative metabolism in the growth-restricted fetus

open access: yesJCI Insight
Fetal growth restriction (FGR) is accompanied by early activation of hepatic glucose production (HGP), a hallmark of type 2 diabetes (T2D). Here, we used fetal hepatic catheterization to directly measure HGP and substrate flux in a sheep FGR model.
Laura D. Brown   +6 more
doaj   +1 more source

TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis

open access: yesThe Journal of Clinical Investigation, 2023
The transcription factor p63 guards genome integrity in the female germline, and its mutations have been reported in patients with premature ovarian insufficiency (POI).
Chengzi Huang   +8 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Studies on the toxicity of Vacor (RH-787) on the reproductive biology of Rattus rattus rufescens [PDF]

open access: yes, 1980
Vacor (RH-787), a relatively new rodenticide, was evaluated for the control of Rattus rattus rufescens. The symptoms of paralysis in hind limbs were observed after feeding it to rodents.
Saxena, Y., Sharma, P. P., Zutshi, M.
core  

The roles of inter- and intra-sexual selection in behavioral isolation between native and invasive pupfishes [PDF]

open access: yes, 2017
Male-male competition and female mate choice may both play important roles in driving and maintaining reproductive isolation between species. When previously allopatric species come into secondary contact with each other due to introductions, they ...
Becher, Cory, Gumm, Jennifer M.
core   +2 more sources

Reproductive Biology Including Evidence for Superfetation in the European Badger Meles meles (Carnivora: Mustelidae)

open access: yesPLoS ONE, 2015
The reproductive biology of the European badger (Meles meles) is of wide interest because it is one of the few mammal species that show delayed implantation and one of only five which are suggested to show superfetation as a reproductive strategy.
L. Corner   +3 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

OSR1 disruption contributes to uterine factor infertility via impaired Müllerian duct development and endometrial receptivity

open access: yesThe Journal of Clinical Investigation, 2023
Three sisters, born from consanguineous parents, manifested a unique Müllerian anomaly characterized by uterine hypoplasia with thin estrogen-unresponsive endometrium and primary amenorrhea, but with spontaneous tubal pregnancies.
Adriana Lofrano-Porto   +17 more
doaj   +1 more source

Length at First Maturity, Spawning TIME, and Reproductive Output in the Females of Hamilton\u27s Anchovy (Thryssa Hamiltonii Gray, 1835) [PDF]

open access: yes, 2020
The Hamilton\u27s anchovy (Thryssa hamiltonii Gray, 1835) is one of main target species in Indonesian small pelagic fishery. This engraulids member is characterized by short lifespan and fast reproductive cycle.
Dewi, N. N. (Nina)   +2 more
core  

Reproductive biology of invasive lionfish (Pterois spp.)

open access: yesFrontiers in Marine Science, 2015
Indo-Pacific lionfishes, Pterois volitans (Linnaeus, 1758) and Pterois miles (Bennett, 1828), native to the Pacific and Indian Oceans, respectively, were first observed in the western Atlantic off Florida in 1985.
Patrick G. Gardner   +3 more
semanticscholar   +1 more source

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