Results 211 to 220 of about 1,879,235 (344)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Reproductive biology of Lasiurus sindicus: a vital perennial fodder grass for arid ecosystem. [PDF]

BMC Plant Biol
Rani R, Sanyal A.
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Exploring the potential of in vitro extracellular vesicle generation in reproductive biology. [PDF]

J Extracell Biol
Franko R, de Almeida Monteiro Melo Ferraz M.   +1 more
europepmc   +1 more source

Genomics and reproductive biology of Leptopilina n. sp. Buffington, Lue, Davis & Tracey sp. nov. (Hymenoptera: Figitidae): An asexual parasitoid of Caribbean Drosophila [PDF]

Amelia R. I. Lindsey, Chia‐Hua Lue, Jeremy S. Davis, Lydia J. Borjon, Stephanie E. Mauthner, Laura C Fricke, Lauren Eads, Maureen E. Murphy, Melissa K. Drown, Christopher Faulk, Matthew L. Buffington, W. Daniel Tracey   +11 more
openalex   +1 more source

Developmental and Reproductive Biology of the Ecto-larval Parasitoid Bracon hebetor Say (Hymenoptera: Braconidae) on Sesame Capsule Borer, Antigastra catalaunalis (Duponchel) (lepidoptera-pyralidae) [PDF]

, 2015
Nesrin El-Basha
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Aspects of the reproductive biology and gonad histology of Pagellus erythrinus (Actinopterygii: perciformes: Sparidae) in the Gulf of Antalya, NE Mediterranean Sea. [PDF]

Vet Res Commun
Balci BA, İkiz R, Arslan MN.
europepmc   +1 more source

Features of the reproductive biology of Rhododendron myrtifolium Schott and Kotschy in the Ukrainian Carpathians and the prospects of introduction

, 2012
M.I. Voloshchuk, M.I. Shumik
openalex   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source