Results 21 to 30 of about 2,140,003 (260)

A single-cell atlas of the myometrium in human parturition

JCI Insight, 2022
Parturition is a well-orchestrated process characterized by increased uterine contractility, cervical ripening, and activation of the chorioamniotic membranes; yet, the transition from a quiescent to a contractile myometrium heralds the onset of labor ...
Roger Pique-Regi, Roberto Romero, Valeria Garcia-Flores, Azam Peyvandipour, Adi L. Tarca, Errile Pusod, Jose Galaz, Derek Miller, Gaurav Bhatti, Robert Para, Tomi Kanninen, Ola Hadaya, Carmen Paredes, Kenichiro Motomura, Jeffrey R. Johnson, Eunjung Jung, Chaur-Dong Hsu, Stanley M. Berry, Nardhy Gomez-Lopez   +18 more
doaj   +1 more source

Radiotherapy exposure directly damages the uterus and causes pregnancy loss

JCI Insight, 2023
Female cancer survivors are significantly more likely to experience infertility than the general population. It is well established that chemotherapy and radiotherapy can damage the ovary and compromise fertility, yet the ability of cancer treatments to ...
Meaghan J. Griffiths, Sarah A. Marshall, Fiona L. Cousins, Lauren R. Alesi, Jordan Higgins, Saranya Giridharan, Urooza C. Sarma, Ellen Menkhorst, Wei Zhou, Alison S. Care, Jacqueline F. Donoghue, Sarah J. Holdsworth-Carson, Peter A.W. Rogers, Evdokia Dimitriadis, Caroline E. Gargett, Sarah A. Robertson, Amy L. Winship, Karla J. Hutt   +17 more
doaj   +1 more source

Placental dysfunction influences fetal monocyte subpopulation gene expression in preterm birth

JCI Insight, 2022
The placenta is the primary organ for immune regulation, nutrient delivery, gas exchange, protection against environmental toxins, and physiologic perturbations during pregnancy.
Abhineet M. Sharma, Robert Birkett, Erika T. Lin, Linda M. Ernst, William A. Grobman, Suchitra Swaminathan, Hiam Abdala-Valencia, Alexander V. Misharin, Elizabeth T. Bartom, Karen K. Mestan   +9 more
doaj   +1 more source

Reproductive and larval biology of the sub-Antarctic hermit crab Pagurus comptus reared in the laboratory [PDF]

, 2006
Fecundity, hatching rhythm, and the planktotrophic larval development of the hermit crab Pagurus comptus from sub-Antarctic waters of the Beagle Channel (Tierra del Fuego) were studied under controlled laboratory conditions of temperature, light cycle ...
Lovrich, Gustavo Alejandro, Thatje, Sven, Lovrich, Gustavo A.   +2 more
core   +1 more source

The Mongolian Gerbil as a Useful Experimental Model in Reproductive Biology

, 2023
Ultimately, the Mongolian gerbils (Meriones unguiculatus) have acquired a relevant role in biological and biomedical experiments alongside other rodents. The use of gerbils in research has been mainly oriented to physiological and pharmacological studies,
Zucão, Mariele Ilario, Perez, Ana Paula Silva, Taboga, Sebastião Roberto, de Campos, Silvana Gisele Pegorin, Ruiz, Thalles Fernando Rocha [UNESP], Zucão, Mariele Ilario [UNESP], Leonel, Ellen Cristina Rivas, Silvana Gisele Pegorin de Campos, Vitor Grigio, Fernanda Cristina Alcântara dos Santos, Vilamaior, Patricia Simone Leite [UNESP], Thalles Fernando Rocha Ruiz, dos Santos, Fernanda Cristina Alcântara, Grigio, Vitor, Vilamaior, Patricia Simone Leite, de Campos, Silvana Gisele Pegorin [UNESP], Taboga, Sebastião Roberto [UNESP], Manoel Francisco Biancardi, Colleta, Simone Jacovaci [UNESP], Grigio, Vitor [UNESP], Biancardi, Manoel Francisco, Colleta, Simone Jacovaci, Rivas Leonel, Ellen, Sebastião Roberto Taboga, Ellen Cristina Rivas Leonel, Ruiz, Thalles Fernando Rocha, Ana Paula Silva Perez, Patricia Simone Leite Vilamaior, Simone Jacovaci Colleta, Mariele Ilario Zucão   +29 more
core   +1 more source

Reproductive biology of Bellucia (MELASTOMATACEAE) [PDF]

Acta Amazonica, 1986
The reproductive biology of five of the seven species of Bellucia (Melastomataceae), a genus of shrubs and small trees, was investigated in Amazonia. Sucessful fruit-set by Bellucia requires floral visitation by bees.
Susanne S. Renner
doaj   +1 more source

Early reproductive investment, senescence and lifetime reproductive success in female Asian elephants [PDF]

, 2014
The evolutionary theory of senescence posits that as the probability of extrinsic mortality increases with age, selection should favour early-life over late-life reproduction.
Hayward, Adam, Hayward, Adam D., Lahdenperä, M, M. Lahdenper €a, Mar, Khyne U., Mar, Khyne U, Lummaa, Virpi, Hayward, AD, A. D. Hayward, K. U. Mar, Mar, KU, Lummaa, V, Lahdenpera, Mirkka, V. Lummaa   +13 more
core   +1 more source

Maternal PlGF and umbilical Dopplers predict pregnancy outcomes at diagnosis of early-onset fetal growth restriction

The Journal of Clinical Investigation, 2023
BACKGROUND Severe, early-onset fetal growth restriction (FGR) causes significant fetal and neonatal mortality and morbidity. Predicting the outcome of affected pregnancies at the time of diagnosis is difficult, thus preventing accurate patient counseling.
Rebecca Spencer, Kasia Maksym, Kurt Hecher, Karel Maršál, Francesc Figueras, Gareth Ambler, Harry Whitwell, Nuno Rocha Nené, Neil J. Sebire, Stefan R. Hansson, Anke Diemert, Jana Brodszki, Eduard Gratacós, Yuval Ginsberg, Tal Weissbach, Donald M. Peebles, Ian Zachary, Neil Marlow, Angela Huertas-Ceballos, Anna L. David   +19 more
doaj   +1 more source

ARRDC5 expression is conserved in mammalian testes and required for normal sperm morphogenesis

Nature Communications, 2023
In sexual reproduction, sperm contribute half the genomic material required for creation of offspring yet core molecular mechanisms essential for their formation are undefined.
Mariana I. Giassetti, Deqiang Miao, Nathan C. Law, Melissa J. Oatley, Julie Park, LeeLa D. Robinson, Lisette A. Maddison, Miranda L. Bernhardt, Jon M. Oatley   +8 more
doaj   +1 more source

Macrophages exert homeostatic actions in pregnancy to protect against preterm birth and fetal inflammatory injury

JCI Insight, 2021
Macrophages are commonly thought to contribute to the pathophysiology of preterm labor by amplifying inflammation — but a protective role has not previously been considered to our knowledge. We hypothesized that given their antiinflammatory capability in
Nardhy Gomez-Lopez, Valeria Garcia-Flores, Peck Yin Chin, Holly M. Groome, Melanie T. Bijland, Kerrilyn R. Diener, Roberto Romero, Sarah A. Robertson   +7 more
doaj   +1 more source