Results 131 to 140 of about 273,699 (263)

Variation in Uterine and Serum Proteins During the Reproductive Cycle in Dairy Cows Following Low and High Dietary Protein Intake. [PDF]

Vet Med Sci
Pirestani A, Motalebipour EZ.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Dynamic regulation of apoptotic and antioxidant pathways throughout the reproductive cycle in female blue swimmer crab. [PDF]

Vet Res Forum
Adhami S, Salamat N, Savari A, Hamidian G.   +3 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Emergence and Return Times in a Colonial, Cave-Dwelling Bat: Age and Sex Differences Driven by Reproductive Cycle. [PDF]

Ecol Evol
Bail NJ, Lumsden LF, Reardon T, van Harten E, Clissold P, Prowse TAA.   +5 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Real-time behavioral monitoring of C57BL/6J mice during reproductive cycle. [PDF]

Front Neurosci
Khatiz A, Tomlinson C, Ruzhytska B, Croft EK, Amrani A, Dunn S, Mendrek A, Gris D.   +7 more
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Nutrition regulates reproductive senescence and terminal investment across the reproductive cycle of a long-lived mammal. [PDF]

Sci Rep
LaSharr TN, Dwinnell SPH, Jakopak RP, Rafferty RT, Randall J, Stewart C, Kaiser R, Thonhoff M, Scurlock B, Fieseler T, Fralick G, Monteith KL.   +11 more
europepmc   +1 more source

Variation in female reproductive tract morphology across the reproductive cycle in the zebra finch. [PDF]

PeerJ, 2020
Hurley LL, Crino OL, Rowe M, Griffith SC.   +3 more
europepmc   +1 more source