Results 131 to 140 of about 289,865 (262)

Alpha/Beta Hydrolase Domain-Containing Protein 2 Regulates the Rhythm of Follicular Maturation and Estrous Stages of the Female Reproductive Cycle. [PDF]

Front Cell Dev Biol, 2021
Björkgren I, Chung DH, Mendoza S, Gabelev-Khasin L, Petersen NT, Modzelewski A, He L, Lishko PV.   +7 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Locality matters: Variation in the reproductive cycle and population structure of subtropical sea urchins. [PDF]

PLoS One
Núñez-González R, Sarmiento-Lezcano AN, Caballero MJ, Tilic E, Castro-Hernández JJ.   +4 more
europepmc   +1 more source

Improving Rabbit Doe Metabolism and Whole Reproductive Cycle Outcomes via Fatty Acid-Rich Moringa oleifera Leaf Extract Supplementation in Free and Nano-Encapsulated Forms. [PDF]

Animals (Basel), 2022
El-Desoky NI, Hashem NM, Elkomy AG, Abo-Elezz ZR.   +3 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Reproductive Cycles and Factors Influencing Reproductive Cycle in Finfish and Their Application for Aquaculture

Fish and shellfish have intricate reproduction cycles that are impacted by a variety of biological and environmental variables. Among the several reproductive techniques used by finfish, especially teleosts, is external fertilization, in which sperm fertilize eggs released into the water column.
openaire   +2 more sources

Variation in Uterine and Serum Proteins During the Reproductive Cycle in Dairy Cows Following Low and High Dietary Protein Intake. [PDF]

Vet Med Sci
Pirestani A, Motalebipour EZ.
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

REPRODUCTIVE CYCLES IN AN EQUATORIAL SPARROW [PDF]

Proceedings of the National Academy of Sciences, 1959
openaire   +2 more sources

Dynamic regulation of apoptotic and antioxidant pathways throughout the reproductive cycle in female blue swimmer crab. [PDF]

Vet Res Forum
Adhami S, Salamat N, Savari A, Hamidian G.   +3 more
europepmc   +1 more source