Results 71 to 80 of about 1,229,803 (292)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Proteomic and metabolomic reveals abnormalities in metabolic processes, epigenetic modifications, oxidative stress, embryonic aneuploidy and implantation in mouse blastocysts derived from in vitro fertilization

Journal of Ovarian Research
Background Assisted reproductive technology (ART), especially in vitro fertilization (IVF), has become an important means of addressing infertility issues.
Jinzhu Song, Yiwen Zhang, Xiaoyu Yin, Xueqi Dong, Hao Tian, Wanting You, Boyang Liu, Keliang Wu, Chuanxin Zhang   +8 more
doaj   +1 more source

Need Assessment and Effect of Sex Education on Awareness and Knowledge among Primary School Students in Klaten, Central Java [PDF]

, 2016
BACKGROUND: Lack of knowledge in reproductive health and weak parental control may have undesired impact on children. There appeared the need of sex education and teaching in reproductive health for school children.
Wartoyo, F. X. (Franciscus)
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Unveiling lipoprotein subfractions signature in high-FNPO PCOS: implications for PCOM diagnosis and risk assessment using advanced machine learning models

BMC Medicine
Background Polycystic ovary syndrome (PCOS) is a common reproductive and metabolic disorder in the reproductive-age women. The international evidence-based guideline for the assessment and management of PCOS 2023 now suggests raising the follicle number ...
Xueqi Yan, Ziyi Yang, Hui Zhao, Gengchen Feng, Shumin Li, Yimeng Li, Yu Sun, Jinlong Ma, Han Zhao, Xueying Gao, Shigang Zhao   +10 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Effect of adding gonadotropin-releasing hormone agonists for luteal support in antagonist cycles on pregnancy outcomes

Scientific Reports
This retrospective cohort study evaluated whether gonadotropin-releasing hormone agonists (GnRHa) used for luteal support during antagonist cycles improved pregnancy outcomes in patients undergoing fresh embryo transfer.
Juan Du, Chang Liu, Ye Zheng, Wei Zhou, Xu Han, Huidan Wang, Xiuqing Zhang, Mei Sun, Xiufang Li   +8 more
doaj   +1 more source

Future Educators’ Gender Norms, Sexuality, and Reproductive Health. [PDF]

, 2013
This investigation explored gender-related norms, sexuality, and reproductive health among education students in a government university in Samar, Philippines.
Cinco, KE, Eclipse, JAL, Eclipse, RAL, Labrague, LJ, Larios, RJP, Laureta, VC, Pescos, JB   +6 more
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source