Results 51 to 60 of about 777,950 (284)

Human chorionic gonadotropin potentially affects pregnancy outcome in women with recurrent implantation failure by regulating the homing preference of regulatory T cells

, 2017
PROBLEM: Human chorionic gonadotropin (hCG) and regulatory T cells (Tregs) have been suggested to play important roles during the initial stage of pregnancy.
Diao, Liang-Hui, Huang, Chun-Yu, Tu, Wen-Wei, Huang, Yong, Zhu, YC, Chen, X, Li, Guan Gui, Zeng, Yong, Zhu, Yuan Chang, Li, Guan-Gui, Li, Yu-Ye, Zhu, Yuan-Chang, Lian, RC, Zhang, Tao, Tu, Wen Wei, Zhang, T, Zeng, Y, Huang, Y, Lian, Ruo-Chun, Li, Yu Ye, Chen, Xian, Lian, Ruo Chun, Diao, Liang Hui, Huang, Chun Yu, Diao, LH, Tu, W, Li, GG, Li, YY, HUANG, C   +28 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Analysis of C3 Gene Variants in Patients With Idiopathic Recurrent Spontaneous Pregnancy Loss

Frontiers in Immunology, 2018
Miscarriage is the most common complication of pregnancy. Approximately 1% of couples trying to conceive will experience recurrent miscarriages, defined as three or more consecutive pregnancy losses and many of these cases remain idiopathic.
Frida C. Mohlin, Piet Gros, Eric Mercier, Jean-Christophe Raymond Gris, Anna M. Blom   +4 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Second Symposium on Reproductive Immunology, Rio de Janeiro, Brazil

, 2010
Universidade Federal de São Paulo, Dept Obstet, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Obstet, São Paulo, BrazilWeb of ...
Daher, Silvia [UNIFESP]
core   +1 more source

COVID-19 and immunomodulation treatment for women with reproductive failures

, 2020
COVID-19 pandemic is affecting various areas of health care, including human reproduction. Many women with reproductive failures, during the peri-implantation period and pregnancy, are on the immunotherapy using immune modulators and immunosuppressant ...
Yang, Xiuhua, Coulam, Carolyn, Ota, Kuniaki, Kwak-Kim, Joanne, Wang, Wen-Juan, Saab, Wael, Won Han, Jae, Han, Aera, Barini, Ricardo, Liao, Aihua, Borges Cavalcante, Marcelo, Huang, Changsheng, Lédée, Nathalie, Takahashi, Toshifumi, Derbala, Youssef, He, Qiaohua, Sung, Nayoung, Lee, Sungki, Bao, Shihua, Cavalcante, Marcelo Borges, Han, Jae Won, Fukui, Atsushi, Alsubki, Lujain   +22 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Celebrating a Century of Microbiology and Immunology [PDF]

, 2019
This brief history captures the last half-century from the last history and features foundational ideas and individuals who played prominent roles through their scientific contributions and leadership in microbiology and immunology at the University of ...
University of Minnesota. Department of Microbiology and Immunology, Hasse, Ashley T.   +1 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The effect of healthy pregnant plasma and preeclamptic plasma on the phagocytosis index of neutrophil granulocytes and monocytes of nonpregnant women

Hypertension in Pregnancy, 2017
Objective: Phagocyte function of neutrophil granulocytes and monocytes is decreased in healthy pregnancy and further decreased in preeclampsia. The cause of the declined function is unknown.
Rudolf Lampé, Ágnes Kövér, Sándor Szűcs, László Pál, Ervin Árnyas, Robert Póka   +5 more
doaj   +1 more source