Results 81 to 90 of about 777,950 (284)

Fetoplacental extracellular vesicles deliver conceptus-derived antigens to maternal secondary lymphoid tissues for immune recognition

JCI Insight
Pregnancy is an immunological paradox where despite a competent maternal immune system, regulatory mechanisms at the fetoplacental interface and maternal secondary lymphoid tissues (SLTs) circumvent rejection of semi-allogeneic concepti.
Juliana S. Powell, Adriana T. Larregina, William J. Shufesky, Mara L.G. Sullivan, Donna Beer Stolz, Stephen J. Gould, Geoffrey Camirand, Sergio D. Catz, Simon C. Watkins, Yoel Sadovsky, Adrian E. Morelli   +10 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

The Self Model and the Conception of Biological Identity in Immunology [PDF]

, 2005
The self/non-self model, first proposed by F.M. Burnet, has dominated immunology for sixty years now. According to this model, any foreign element will trigger an immune reaction in an organism, whereas endogenous elements will not, in normal ...
Pradeu, Thomas, Carosella, Edgardo,, Carosella, Edgardo, D., Carosella, Edgardo D., Thomas Pradeu, Edgardo D. Carosella   +5 more
core   +1 more source

Evaluating the Impact of Female Factors on Specific Stages of Early Embryo Development: A Retrospective Analysis of 1372 IVF Cycles

International Journal of Women's Health
Huan Jiang,1 Xiaolu Xia,1 Biyun Zhang,2 Haiyan Pan,3 Ying Luo,4 Shihao Qu,5 Jianying Xu4 1Department of Reproductive Endocrinology, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Affiliated Shenzhen Women and Children’s ...
Jiang H, Xia X, Zhang B, Pan H, Luo Y, Qu S, Xu J   +6 more
doaj  

Distinct transcriptional and epigenomic programs define Hofbauer cells in term placenta

JCI Insight
Hofbauer cells (HBCs) are fetal macrophages located in the placenta that contribute to antimicrobial defense, angiogenesis, tissue remodeling, and metabolic processes within the chorionic villi.
Benjámin R. Baráth, Dóra Bojcsuk, Krisztian Bene, Noemí Caballero-Sánchez, Tímea Cseh, João CR. de Freitas, Petros Tzerpos, Marta Toth, Zhonghua Tang, Seth Guller, Zoárd Tibor Krasznai, Patrícia Neuperger, Gabor J. Szebeni, Gergely Nagy, Tamás Deli, Laszlo Nagy   +15 more
doaj   +1 more source

The effect of latent Mycobacterium tuberculosis infection on ovarian reserve and pregnancy outcomes among infertile women in China

BMC Infectious Diseases
Background Latent Mycobacterium tuberculosis infection (LTBI) is common among patients with infertility, yet its effects on ovarian reserve function and pregnancy outcomes in women undergoing assisted reproductive technology (ART) remain unclear.
Xiaobing Yang, Haitian Chen, Xiangyi Kong, Taisheng Lai, Hailong Liang, Zhihao Chen, Tonghua Wu, Meilan Mo, Yuye Li   +8 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Pathogenetical and clinical aspects of antis perm immunity

, 1999
Reproductive Immunology is a compilation of research articles presented during the VII International Congress of Reproductive Immunology which was held in New Delhi, India on 27-30 October 1998.
Francesco Lombardo, LENZI, Andrea, LOMBARDO, Francesco, Loredana Gandini, Paola Lauretti, Andrea Lenzi, A. Filippini, GANDINI, Loredana, P. Lauretti, Antonio Filippini, DONDERO, Franco, ZIPARO, Elio, Elio Ziparo, Franco Dondero   +13 more
core   +1 more source

Treg cells promote decidual vascular remodeling and modulate uterine NK cells in pregnant mice

JCI Insight
Regulatory T (Treg) cells are essential for maternal immune tolerance of the fetus and placenta. In preeclampsia, aberrant Treg cell tolerance is implicated, but how Treg cells affect the uterine vascular dysfunction thought to precede placental ...
Shanna L. Hosking, Lachlan M. Moldenhauer, Ha M. Tran, Hon Y. Chan, Holly M. Groome, Evangeline A.K. Lovell, Ella S. Green, Stephanie E. O’Hara, Claire T. Roberts, Kerrie L. Foyle, Sandra T. Davidge, Sarah A. Robertson, Alison S. Care   +12 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source