Results 161 to 170 of about 147,088 (237)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Replicate geographic transects across a hybrid zone reveal parallelism and differences in the genetic architecture of reproductive isolation. [PDF]

Evol Lett
Semenov G, Kenyon H, Funk E, Anderson W, McQuillan M, Spinelli J, Russell A, Martinez N, Van Huynh A, Alexander A, Schweizer R, Linck E, Cheviron Z, Carling M, Roth T, Robbins M, Rice A, Taylor S.   +17 more
europepmc   +1 more source

Widespread Gene Expression Divergence in Butterfly Sensory Tissues Plays a Fundamental Role During Reproductive Isolation and Speciation. [PDF]

Mol Biol Evol, 2022
Wu N, Evans E, van Schooten B, Meléndez-Rosa J, Ortiz Y, Planas Soto-Navarro SM, Van Belleghem SM, Counterman BA, Papa R, Zhang W.   +9 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Widespread genomic signatures of reproductive isolation and sex-specific selection in the Eastern Yellow Robin, Eopsaltria australis. [PDF]

G3 (Bethesda), 2022
Kvistad L, Falk S, Austin L.
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Pollination niche shifts in sympatric globular cacti <i>Eriosyce</i>: Consequences on reproductive isolation and species formation. [PDF]

Plant Divers
Guerrero PC, Martínez-Harms J, Arroyo MTK, Eaton D, Meriño BM, Varas-Myrik A, Villalobos-Barrantes HM, Carvallo GO.   +7 more
europepmc   +1 more source

Reproductive isolation via polygenic local adaptation in sub-divided populations: Effect of linkage disequilibria and drift. [PDF]

PLoS Genet, 2022
Sachdeva H.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Reproductive Isolating Mechanisms and Speciation

JOURNAL OF SCIENTIFIC RESEARCH, 2022
openaire   +1 more source