Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Reproductive rights for women with chronic kidney disease. Unfortunately, we are still in our infancy. [PDF]
J Bras Nefrol, 2023 Luders C.
europepmc +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
The State of the States: Targeted Regulation of Abortion Providers in 2013 [PDF]
, 2014 The State of the States focuses on laws enacted in 2013 in four categories of abortion restrictions that the Center identifies as the most significant trends: abortion bans, restrictions on medication abortion, restrictions on insurance coverage for ...
core
The Rule of Law for the Exercise of Marriage and Reproductive Rights for Women with Intellectual Disabilities in China. [PDF]
Risk Manag Healthc Policy, 2022 Huang Z, Chen B, Feng Z.
europepmc +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
'The law is very, very outdated and not keeping up with the technology': novel forms of assisted gestation, legal challenges, and perspectives of reproductive rights advocates in England and Wales. [PDF]
J Law Biosci, 2023 Romanis EC.
europepmc +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Debilitated Lifeworlds: Women's Narratives of Forced Sterilization as Delinking from Reproductive Rights. [PDF]
Med Anthropol Q, 2022 Chaparro-Buitrago J.
europepmc +1 more source
Formal Equality in Law, Moral Regulation in Practice: Courts Versus Policy Makers as Champions of Sexuality and Reproductive Rights in Canada [PDF]
, 2011 Linda A. White
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