Results 91 to 100 of about 562,482 (333)

Eugenics [PDF]

The main concern of the first eugenists, such as Karl Pearson and Walter Weldon of University College London , were the perceived intelligence factors considered to be correlated with the social class.
Sfetcu, Nicolae
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Mortality, protoplasm decay rate, and reliability of staining techniques to recognise 'living' foraminifera: a review.

, 2000
Non-vital staining, especially with rose Bengal, has been widely used in ecological studies to differentiate between the tests of dead(unstained) foraminifera from those presumed to be living at the time of collection (stained).
Bowser, S.S., Murray, J.W.
core  

Gonad development and reproduction in the monoecious species Chlorophthalmus agassizi (Actinopterygii: Aulopiformes: Chlorophthalmidae) from the Sardinian Waters (Central-Western Mediterranean) [PDF]

, 2010
Background. The shortnose greeneye, Chlorophthalmus agassizi Bonaparte, 1840, is a species with a circumglobal distribution and is among the most abundant commercial fishes in some Mediterranean areas.
Cabiddu S, Cau A, Follesa MC, Porcu C
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Trends and factors associated with skilled birth attendance in a post-Ebola context: DHS Guinea 2018

Journal of Public Health in Africa
Background: In Guinea, the 2013–2015 Ebola epidemic profoundly affected maternal health service use. The frequency of births attended by skilled health professionals in the post-Ebola context remains under-documented.
Madeleine Toure, Fanta Barry, Tiany Sidibe, Sadan Camara, Ramata Diallo, Kaba Saran Keita, Maimouna Balde, Bienvenu Salim Camara, Karifa Kourouma, Mamadou Dioulde Balde   +9 more
doaj   +1 more source

ESHRE task force on ethics and law 15: Cross-border reproductive care [PDF]

, 2008
This paper analyses the ethical aspects of cross-border reproductive care. Ethical questions are raised by some of the main reasons of cross-border travelling, i.e. law evasion and unequal access to treatment.
Cohen, J., de Wert, G., Devroey, P., Pennings, Guido, Shenfield, F., Tarlatzis, B.   +5 more
core   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source