Results 211 to 220 of about 219,005 (309)

Construction of an Adverse Outcome Pathway Framework for Glyphosate-Induced Female Reproductive Toxicity Based on Toxicity Pathways. [PDF]

Environ Health (Wash)
Peng B, Schlenk D, Liu J.
europepmc   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Gut microbiota mitigate the reproductive toxicity of silver nanoparticles through thiamine-derived metabolites. [PDF]

Nat Commun
Gong JX, Wang XL, Lin CX, Li XY, Wu J, Tan QG, Yang L, Miao AJ.   +7 more
europepmc   +1 more source

Rapid Sintering of Porous Organic Polymer Powders Into Mechanically Strong Monoliths for Efficient CO2 Capture

Advanced Functional Materials, EarlyView.
Spark plasma sintering enables rapid processing of porous organic polymer (POP) from fine powders to a freestanding and mechanically robust monolith. The sintering process retains the CO2 adsorption capacity and CO2/N2 selectivity, making the monolith more suitable as a solid sorbent for practical carbon capture applications.
Duan Li, Tianhui Shi, Sirui Ran, Lei Zeng, Chao Xu   +4 more
wiley   +1 more source

Protective role of baicalin against methylparaben-induced reproductive toxicity: Insights into hormonal and enzymatic regulation. [PDF]

Toxicol Rep
Akaahan DI, Agu AU, Anyanwu NC, Orjiako VO, Anyanwu GE.   +4 more
europepmc   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Biotic Transformation of Abiotically Stable Nanoscale UiO-66 Metal-Organic Framework by <i>Daphnia magna</i> Results in Chronic Reproductive Toxicity. [PDF]

ACS Nano
Chakraborty S, Dhumal P, Mikulska I, Pham S, Ellis Bradford LJ, Menon D, Misra SK, Lynch I.   +7 more
europepmc   +1 more source

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

Endocrine disruption rewards: bisphenol-A-induced reproductive toxicity and the precision ameliorative potential of flavonoids in preclinical studies. A systematic review and meta-analysis. [PDF]

Front Toxicol
Okon MB, Fasogbon IV, Swase D, Dangana RS, Makena W, Ojiakor VO, Etukudo EM, Chebet J, Musyoka AM, Ifie SE, Mbyemeire H, Mbina SA, Ugwu OP, Oviosun A, Usman IM, Ifie JE, Rangasamy L, Olorunnisola OS, Mounmbegna P, Noreen S, Aja PM.   +20 more
europepmc   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source